Reactome | U2AF2 [nucleoplasm]

U2AF2 [nucleoplasm]

Stable Identifier

R-SSC-71987

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

U2AF2, A0A481APG3

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - Transport of Mature Transcript to Cytoplasm (Sus scrofa)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Sus scrofa)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Sus scrofa)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Sus scrofa)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
  - mRNA 3'-end processing (Sus scrofa)
    - TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Sus scrofa)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
      - Spliced mRNP [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
    - mRNA Polyadenylation (Sus scrofa)
      - Core CPA complex binds capped pre-mRNA (Sus scrofa)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
      - PP1 dephosphorylates RNA Pol II (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
      - RBBP6 activates CPSF complex (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
  - mRNA Splicing (Sus scrofa)
    - mRNA Splicing - Major Pathway (Sus scrofa)
      - Formation of the Spliceosomal E complex (Sus scrofa)
        
        Spliceosomal E complex [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)
        
        U2AF [nucleoplasm] (Sus scrofa)
        
        U2AF2 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A481APG3

Gene Names

U2AF2

Reference Genes

BioGPS Gene:102167536 U2AF2

ENSEMBL:ENSSSCG00000034815.3

Monarch:102167536 U2AF2

NCBI Gene:102167536 U2AF2

UCSC:A0A481APG3 U2AF2

Reference Transcript

RefSeq:XM_021093447.1 U2AF2

Other Identifiers

102167536

GO:0000243

GO:0000245

GO:0000398

GO:0000974

GO:0003676

GO:0003723

GO:0005634

GO:0005681

GO:0006397

GO:0008187

GO:0008380

GO:0016071

GO:0016607

GO:0019899

GO:0030628

GO:0031397

GO:0033120

GO:0048025

GO:0065003

GO:0070742

GO:0071004

GO:0089701

Ssc.6204.2.S1_at

Participates

as an input of

JMJD6 dimer hydroxylates lysine residues of U2AF2 (Sus scrofa)

as a component of

Other forms of this molecule

U2AF2 [nucleoplasm]

Inferred From

U2AF2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020949106.1

ENSEMBL

ENSSSCG00000034815, ENSSSCT00000063346, ENSSSCP00000042718

VGNC

94623

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