Reactome | HNRNPL [nucleoplasm]

HNRNPL [nucleoplasm]

Stable Identifier

R-SSC-71947

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

HNRNPL, A0A287AJX7

Locations in the PathwayBrowser

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Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - Formation of pre-mRNPs (Sus scrofa)
    - Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
      - shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
      - Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
  - mRNA 3'-end processing (Sus scrofa)
    - mRNA Polyadenylation (Sus scrofa)
      - Core CPA complex binds capped pre-mRNA (Sus scrofa)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - PP1 dephosphorylates RNA Pol II (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - RBBP6 activates CPSF complex (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
  - mRNA Splicing (Sus scrofa)
    - mRNA Splicing - Major Pathway (Sus scrofa)
      - Formation of the Spliceosomal C complex containing intron lariat (Sus scrofa)
        
        Spliceosomal B* complex [nucleoplasm] (Sus scrofa)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Spliceosomal C complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal C* complex (Sus scrofa)
        
        Spliceosomal C complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal E complex (Sus scrofa)
        
        Spliceosomal E complex [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal P complex and exon ligation (Sus scrofa)
        
        Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        Spliceosomal P complex [nucleoplasm] (Sus scrofa)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
      - Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Sus scrofa)
        
        Spliceosomal P complex [nucleoplasm] (Sus scrofa)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPL [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AJX7

Gene Names

HNRNPL

Reference Genes

ENSEMBL:ENSSSCG00000035570.3

UCSC:A0A287AJX7 HNRNPL

Other Identifiers

102163392

GO:0000381

GO:0000785

GO:0000976

GO:0003676

GO:0003723

GO:0003729

GO:0005634

GO:0005654

GO:0005737

GO:0006355

GO:0006397

GO:0016071

GO:0035770

GO:0043226

GO:0043484

GO:0045120

GO:0045202

GO:0045892

GO:0097157

GO:1990904

Ssc.16767.1.S1_at

Participates

as a member of

shuttling HNRNPs [nucleoplasm] (Sus scrofa)

Inferred From

HNRNPL [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCT00000061924, ENSSSCG00000035570, ENSSSCP00000044313

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