Reactome | HNRNPK [nucleoplasm]

HNRNPK [nucleoplasm]

Stable Identifier

R-SSC-71945

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

HNRNPK, A0A4X1UTE2

Locations in the PathwayBrowser

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Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - Formation of pre-mRNPs (Sus scrofa)
    - Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
      - shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
      - Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
  - mRNA 3'-end processing (Sus scrofa)
    - mRNA Polyadenylation (Sus scrofa)
      - Core CPA complex binds capped pre-mRNA (Sus scrofa)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - PP1 dephosphorylates RNA Pol II (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - RBBP6 activates CPSF complex (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
  - mRNA Splicing (Sus scrofa)
    - mRNA Splicing - Major Pathway (Sus scrofa)
      - Formation of the Spliceosomal C complex containing intron lariat (Sus scrofa)
        
        Spliceosomal B* complex [nucleoplasm] (Sus scrofa)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Spliceosomal C complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal C* complex (Sus scrofa)
        
        Spliceosomal C complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal E complex (Sus scrofa)
        
        Spliceosomal E complex [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - Formation of the Spliceosomal P complex and exon ligation (Sus scrofa)
        
        Spliceosomal C* complex [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        Spliceosomal P complex [nucleoplasm] (Sus scrofa)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
      - Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Sus scrofa)
        
        Spliceosomal P complex [nucleoplasm] (Sus scrofa)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Sus scrofa)
        
        Alternative Splicing Factors [nucleoplasm] (Sus scrofa)
        
        shuttling HNRNPs [nucleoplasm] (Sus scrofa)
        
        HNRNPK [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A4X1UTE2

Gene Names

HNRNPK

Reference Genes

BioGPS Gene:100622191 HNRNPK

ENSEMBL:ENSSSCG00000022760.4

Monarch:100622191 HNRNPK

NCBI Gene:100622191 HNRNPK

UCSC:A0A4X1UTE2 HNRNPK

Reference Transcript

Other Identifiers

100622191

GO:0000785

GO:0002102

GO:0003676

GO:0003677

GO:0003723

GO:0003729

GO:0005634

GO:0005654

GO:0005681

GO:0005737

GO:0006325

GO:0006355

GO:0006357

GO:0006397

GO:0008380

GO:0010494

GO:0010629

GO:0016071

GO:0019904

GO:0031047

GO:0031048

GO:0042802

GO:0042981

GO:0043066

GO:0043226

GO:0045892

GO:0045944

GO:0048024

GO:0048025

GO:0051253

GO:0060816

GO:0071013

GO:1902165

GO:1905581

GO:1990904

Ssc.16654.1.A1_at

Ssc.16654.1.A2_at

Participates

as an input of

CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Sus scrofa)

as a member of

shuttling HNRNPs [nucleoplasm] (Sus scrofa)

Other forms of this molecule

HNRNPK [nucleoplasm]

Inferred From

HNRNPK [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020919671.1, XP_020919673.1, XP_020919672.1, XP_020919674.1, XP_020919675.1, XP_020919669.1

ENSEMBL

ENSSSCG00000022760, ENSSSCP00000026450, ENSSSCT00000025854

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