Reactome | CCNA2 [nucleoplasm]

CCNA2 [nucleoplasm]

Stable Identifier

R-SSC-68905

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

CCNA2, D5HP13

Locations in the PathwayBrowser

Expand all

DNA Repair (Sus scrofa)

- DNA Double-Strand Break Repair (Sus scrofa)
  - Homology Directed Repair (Sus scrofa)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
      - Processing of DNA double-strand break ends (Sus scrofa)
        
        CDK2 phosphorylates RBBP8 (Sus scrofa)
        
        CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)
        
        DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Sus scrofa)
        
        CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)
        
        MRN complex binds CDK2 and RBBP8 (Sus scrofa)
        
        CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)
        
        DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Sus scrofa)
        
        CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - Transcriptional Regulation by TP53 (Sus scrofa)
      - Regulation of TP53 Activity (Sus scrofa)
        
        Regulation of TP53 Activity through Phosphorylation (Sus scrofa)
        
        CDK2 phosphorylates TP53 (Sus scrofa)
        
        CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)
        
        Regulation of TP53 Expression and Degradation (Sus scrofa)
        
        Regulation of TP53 Degradation (Sus scrofa)
        
        (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Sus scrofa)
        
        CCNA:p-CDK1/2 [nucleoplasm] (Sus scrofa)
        
        CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)
        
        CCNA:p-T161-CDK1 [nucleoplasm] (Sus scrofa)
        
        CCNA2:p-T161-CDK1 [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)
      - TP53 Regulates Transcription of Cell Cycle Genes (Sus scrofa)
        
        TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Sus scrofa)
        
        Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Sus scrofa)
        
        CCNA:CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)
        
        Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Sus scrofa)
        
        CCNA:CDK2 [nucleoplasm] (Sus scrofa)
        
        CCNA [nucleoplasm] (Sus scrofa)
        
        CCNA2 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:D5HP13

Gene Names

CCNA2

Reference Genes

BioGPS Gene:100415929 CCNA2

ENSEMBL:ENSSSCG00000060144.1

KEGG:ssc:100415929 CCNA2

Monarch:100415929 CCNA2

NCBI Gene:100415929 CCNA2

UCSC:D5HP13 CCNA2

Reference Transcript

RefSeq:NM_001177926.1 CCNA2

Other Identifiers

100415929

GO:0000082

GO:0000086

GO:0000307

GO:0001939

GO:0001940

GO:0005634

GO:0005654

GO:0005737

GO:0005815

GO:0005829

GO:0006275

GO:0006351

GO:0006355

GO:0007265

GO:0016538

GO:0019901

GO:0019904

GO:0043687

GO:0044772

GO:0044843

GO:0045893

GO:0051301

GO:0097122

GO:0097124

Ssc.23877.1.S1_at

Ssc.23877.2.A1_at

Participates

as a member of

CCNA1,CCNA2 [nucleoplasm] (Sus scrofa)

as a component of

as a candidate of

CCNA [nucleoplasm] (Sus scrofa)

Other forms of this molecule

CCNA2 [nucleoplasm]

CCNA2 [cytosol]

phospho-CCNA2 [cytosol]

phospho-CCNA2 [nucleoplasm]

Inferred From

CCNA2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001171397.1

ENSEMBL

ENSSSCT00000081990, ENSSSCP00000066861, ENSSSCG00000060144

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