Reactome | PPL [cytosol]

PPL [cytosol]

Stable Identifier

R-SSC-6810850

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

PPL, F1RK90

Locations in the PathwayBrowser

Expand all

Developmental Biology (Sus scrofa)

- Keratinization (Sus scrofa)
  - Formation of the cornified envelope (Sus scrofa)
    - CASP14 cleaves filaggrin (Sus scrofa)
      - Late cornified envelope [plasma membrane] (Sus scrofa)
        
        Cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:IVL:TGM1:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:IVL:TGM1:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
    - CDSN binds the cornified envelope (Sus scrofa)
      - Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:IVL:TGM1:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
      - Cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:IVL:TGM1:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
    - EVL:PPL heterodimer binds the inner surface of the plasma membrane (Sus scrofa)
      - EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
      - EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
    - Envoplakin binds periplakin (Sus scrofa)
      - EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
      - PPL [cytosol] (Sus scrofa)
    - Kazrin binds periplakin (Sus scrofa)
      - KAZN:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
      - PPL [cytosol] (Sus scrofa)
    - Lamellar bodies bind the early cornified envelope (Sus scrofa)
      - Cornified envelope [plasma membrane] (Sus scrofa)
        
        Early cornified envelope [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:IVL:TGM1:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
      - Early cornified envelope [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:IVL:TGM1:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)
    - Plasma membrane resorption (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:IVL:TGM1:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL:Cell surface [plasma membrane] (Sus scrofa)
        
        EVPL:PPL [cytosol] (Sus scrofa)
        
        PPL [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RK90

Gene Names

PPL

Reference Genes

BioGPS Gene:100512773 PPL

ENSEMBL:ENSSSCG00000007927.5

KEGG:ssc:100512773 PPL

Monarch:100512773 PPL

NCBI Gene:100512773 PPL

UCSC:F1RK90 PPL

Reference Transcript

RefSeq:XM_003124640.4 PPL

Other Identifiers

100512773

GO:0001533

GO:0005198

GO:0005737

GO:0005856

GO:0005882

GO:0005886

GO:0007010

GO:0009612

GO:0016020

GO:0030057

GO:0031424

GO:0042060

GO:0045104

GO:0070161

Ssc.25395.1.S1_at

Participates

as an input of

as a component of

Other forms of this molecule

PPL [cornified envelope]

Inferred From

PPL [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_003124688.4

ENSEMBL

ENSSSCP00000008464, ENSSSCG00000007927, ENSSSCT00000008688

VGNC

91702