Reactome | TMED3 [transport vesicle]

TMED3 [transport vesicle]

Stable Identifier

R-SSC-6808874

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

transport vesicle

Synonyms

TMED3, F1RKR4

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPI-mediated anterograde transport (Sus scrofa)
        
        ARFGAPs stimulate ARF GTPase activity (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPI-mediated anterograde transport (Sus scrofa)
      - ARFGAPs stimulate ARF GTPase activity (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Sus scrofa)
    - Golgi-to-ER retrograde transport (Sus scrofa)
      - COPI-dependent Golgi-to-ER retrograde traffic (Sus scrofa)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Sus scrofa)
        
        p24 dimers [transport vesicle] (Sus scrofa)
        
        TMED3 dimer [transport vesicle] (Sus scrofa)
        
        TMED3 [transport vesicle] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RKR4

Gene Names

TMED3

Reference Genes

ENSEMBL:ENSSSCG00000001773.5

Other Identifiers

100155219

GO:0005737

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0006886

GO:0006888

GO:0007030

GO:0015031

GO:0016020

GO:0016192

GO:0030126

GO:0030134

GO:0031410

GO:0033116

GO:0043226

GO:0043231

Ssc.15738.1.S1_at

Participates

as a component of

TMED3 dimer [transport vesicle] (Sus scrofa)

Other forms of this molecule

TMED3 [endoplasmic reticulum membrane]

TMED3 [endoplasmic reticulum-Golgi intermediate compartment membrane]

TMED3 [Golgi membrane]

Inferred From

TMED3 [transport vesicle] (Homo sapiens)

Cross References

OpenTargets

ENSG00000166557

Ensembl

ENSSSCP00000001939, ENSSSCG00000001773, ENSSSCT00000001988

VGNC

94055

Cite Us!