Reactome | NDUFA13 [mitochondrial inner membrane]

NDUFA13 [mitochondrial inner membrane]

Stable Identifier

R-SSC-59936

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

mitochondrial inner membrane

Synonyms

NDUFA13, A0A8D1NRT6

Locations in the PathwayBrowser

Expand all

Metabolism (Sus scrofa)

- Aerobic respiration and respiratory electron transport (Sus scrofa)
  - Respiratory electron transport (Sus scrofa)
    - Complex I biogenesis (Sus scrofa)
      - Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
      - Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
      - The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
      - The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)
    - Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Sus scrofa)
      - Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA13 [mitochondrial inner membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A8D1NRT6

Gene Names

NDUFA13

Reference Genes

BioGPS Gene:100622110 NDUFA13

ENSEMBL:ENSSSCG00000056961.1

KEGG:ssc:100622110 NDUFA13

Monarch:100622110 NDUFA13

NCBI Gene:100622110 NDUFA13

UCSC:A0A8D1NRT6 NDUFA13

Reference Transcript

RefSeq:NM_001244646.1 NDUFA13

Other Identifiers

100622110

GO:0005739

GO:0005743

GO:0016020

GO:0045271

Ssc.2029.1.S1_at

Participates

as an input of

HTRA2 binds NDUFA13 (GRIM-19) (Sus scrofa)

as a component of

Other forms of this molecule

NDUFA13 [mitochondrial inner membrane]

Inferred From

NDUFA13 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001231575.1

ENSEMBL

ENSSSCP00000081245, ENSSSCT00000093517, ENSSSCG00000056961

PDB

7VYG, 7VYS, 7VZW, 7W1Z, 7VYE, 7VBZ, 5GUP, 7VC0, 7W4C, 7VYH, 7W4J, 7VWL, 7W2R, 7VY9, 7W35, 7VBP, 7VZ1, 7W00, 7W4E, 7V33, 7W4Q, 7VBN, 7VYA, 7VY1, 7W20, 7VXU, 7W4F, 7V3M, 7V2F, 7V2C, 5GPN, 7V32, 7W0R, 7V2K, 7W32, 7W4L, 7VYI, 7W2L, 7W2K, 7W1T, 7W1V, 7W1U, 7VZV, 7VWJ, 7W2Y, 7VYF, 7W2U, 7W1P, 7W4K, 7V2H, 7VYN, 7VBL, 7V2R, 7V2D, 7V31, 7W1O, 9CE2, 7VB7, 7V2E, 7W4M, 7W0Y, 7VXS, 7W4D, 7VY8, 7V30, 7W4G, 7W31, 7W4N, 7W0H, 7VZ8, 7VXP