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MAPK3 [cytosol]
Stable Identifier
R-SSC-59284
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
A0A480NH74
Locations in the PathwayBrowser
Expand all
Hemostasis (Sus scrofa)
Platelet activation, signaling and aggregation (Sus scrofa)
Thrombin signalling through proteinase activated receptors (PARs) (Sus scrofa)
Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Sus scrofa)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
F2R:ARRB1 binds MAPKs, SRC-1 (Sus scrofa)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
F2R:ARRB2 binds MAPKs, SRC-1 (Sus scrofa)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
SRC-1 bound to ARRB2 is not activated (Sus scrofa)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Sus scrofa)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Growth hormone receptor signaling (Sus scrofa)
Lyn activates ERK (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Interferon Signaling (Sus scrofa)
Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
ISG15 antiviral mechanism (Sus scrofa)
ISGylation of host proteins (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
ISGylated host proteins [cytosol] (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
ISGylated host proteins [cytosol] (Sus scrofa)
ISG15 targets [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Interferon gamma signaling (Sus scrofa)
IFNG signaling activates MAPKs (Sus scrofa)
JAK1-activated RAF1 phosphorylates MAPKs (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF-independent MAPK1/3 activation (Sus scrofa)
Cytosolic DUSPs dephosphorylate MAPKs (Sus scrofa)
MAPK monomers and dimers [cytosol] (Sus scrofa)
MAPK3 dimer [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
MAP2K and MAPK activation (Sus scrofa)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Dual mechanism MAPK inhibitors bind MAPKs (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
IL17RD binds p-2S MAP2Ks and MAPKs (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAP2Ks and MAPKs bind to the activated RAF complex (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
RAF phosphorylates MAP2K dimer (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Negative regulation of MAPK pathway (Sus scrofa)
Cytosolic DUSPs dephosphorylate MAPKs (Sus scrofa)
MAPK monomers and dimers [cytosol] (Sus scrofa)
MAPK3 dimer [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by Insulin receptor (Sus scrofa)
Insulin receptor signalling cascade (Sus scrofa)
Signal attenuation (Sus scrofa)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Sus scrofa)
MAPK3,(MAPK1) [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Sus scrofa)
MAPK3,(MAPK1) [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Signaling by NTRKs (Sus scrofa)
Signaling by NTRK1 (TRKA) (Sus scrofa)
Signalling to ERKs (Sus scrofa)
Prolonged ERK activation events (Sus scrofa)
Frs2-mediated activation (Sus scrofa)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK3 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A480NH74
Reference Genes
ENSEMBL:ENSSSCG00000040682.3
Other Identifiers
445013
GO:0000165
GO:0000166
GO:0001784
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005524
GO:0005634
GO:0005635
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005794
GO:0005829
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006351
GO:0006355
GO:0006468
GO:0006914
GO:0006974
GO:0007010
GO:0008286
GO:0009887
GO:0010759
GO:0014032
GO:0014044
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0019233
GO:0019902
GO:0023052
GO:0030154
GO:0030278
GO:0030509
GO:0030641
GO:0030878
GO:0031143
GO:0031410
GO:0031663
GO:0032200
GO:0032212
GO:0032496
GO:0032872
GO:0034198
GO:0034614
GO:0036211
GO:0038133
GO:0042473
GO:0042552
GO:0042770
GO:0042802
GO:0043226
GO:0043330
GO:0045944
GO:0048009
GO:0048538
GO:0048856
GO:0048870
GO:0050804
GO:0050877
GO:0051216
GO:0051403
GO:0051493
GO:0060020
GO:0060324
GO:0060425
GO:0060440
GO:0061308
GO:0070371
GO:0070374
GO:0070498
GO:0070849
GO:0071260
GO:0071276
GO:0071356
GO:0072584
GO:0090170
GO:0098542
GO:0098792
GO:0098978
GO:0120041
GO:0140096
GO:0140297
GO:1904262
GO:1904355
GO:1904417
GO:2000641
Ssc.5924.1.S1_at
Participates
as a member of
ISG15 targets [cytosol] (Sus scrofa)
MAPK3,(MAPK1) [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
as a component of
MAPK3 dimer [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-p-Y204-MAPK3-3 [cytosol]
MAPK3 [nucleoplasm]
phospho-p-T202,Y204-MAPK3 [cytosol]
phospho-p-T202,Y204-MAPK3 [nucleoplasm]
Inferred From
MAPK3 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSSSCT00000098126
,
ENSSSCG00000040682
,
ENSSSCP00000080176
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