Reactome | phospho-H3-3A [nucleoplasm]

phospho-H3-3A [nucleoplasm]

Stable Identifier

R-SSC-5625858

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

p-T12,MeK-H3F3A, Q71LE2

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
  - Signaling by Rho GTPases (Sus scrofa)
    - RHO GTPase Effectors (Sus scrofa)
      - RHO GTPases activate PKNs (Sus scrofa)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Sus scrofa)
        
        KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        phospho-H3-3A [nucleoplasm] (Sus scrofa)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
        
        phospho-H3-3A [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:Q71LE2

Gene Names

H3-3A

Reference Genes

BioGPS Gene:100521680 H3-3A

BioGPS Gene:396970 H3-3A

ENSEMBL:ENSSSCG00000017202.3 H3-3A

ENSEMBL:ENSSSCG00000023971

ENSEMBL:ENSSSCG00000023971.4 H3-3A

ENSEMBL:ENSSSCG00005011893.1 H3-3A

ENSEMBL:ENSSSCG00015036810.1 H3-3A

ENSEMBL:ENSSSCG00015048325.1 H3-3A

ENSEMBL:ENSSSCG00025037271.1 H3-3A

ENSEMBL:ENSSSCG00030005134.1 H3-3A

ENSEMBL:ENSSSCG00035048727.1 H3-3A

ENSEMBL:ENSSSCG00035053743.1 H3-3A

ENSEMBL:ENSSSCG00040044657.1 H3-3A

ENSEMBL:ENSSSCG00040071581.1 H3-3A

ENSEMBL:ENSSSCG00045029396.1 H3-3A

ENSEMBL:ENSSSCG00045038628.1 H3-3A

ENSEMBL:ENSSSCG00050017758.1 H3-3A

ENSEMBL:ENSSSCG00050070605.1 H3-3A

ENSEMBL:ENSSSCG00055006012.1 H3-3A

ENSEMBL:ENSSSCG00055013826.1 H3-3A

ENSEMBL:ENSSSCG00060029017.1 H3-3A

ENSEMBL:ENSSSCG00060069290.1 H3-3A

ENSEMBL:ENSSSCG00065030240.1 H3-3A

ENSEMBL:ENSSSCG00065055858.1 H3-3A

ENSEMBL:ENSSSCG00070007464.1 H3-3A

ENSEMBL:ENSSSCG00070020711.1 H3-3A

KEGG Gene (Sus scrofa):100521680 H3-3A

KEGG Gene (Sus scrofa):396970 H3-3A

Monarch:100521680 H3-3A

Monarch:396970 H3-3A

NCBI Gene:100521680 H3-3A

NCBI Gene:396970 H3-3A

Reference Transcript

Other Identifiers

100521680

396970

GO:0000228

GO:0000775

GO:0000785

GO:0000939

GO:0001556

GO:0001649

GO:0001740

GO:0005634

GO:0005694

GO:0006325

GO:0006997

GO:0007283

GO:0007286

GO:0007338

GO:0007566

GO:0008283

GO:0008584

GO:0022414

GO:0030154

GO:0031047

GO:0031508

GO:0031509

GO:0032200

GO:0035264

GO:0042692

GO:0043226

GO:0048477

GO:0048856

GO:0065003

GO:0090230

GO:1902340

Ssc.10940.1.S1_at

Ssc.11548.1.S1_at

Ssc.11548.1.S2_at

Participates

as a member of

p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)

Other forms of this molecule

H3-3A [nucleoplasm]

phospho-H3-3A [nucleoplasm]

H3-3A [nucleoplasm]

phospho-H3-3A [nucleoplasm]

H3-3A [nucleoplasm]

Inferred From

p-T12,MeK-H3F3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-methyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6-methyl-L-lysine [MOD:00085]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

XP_003131242.1, NP_999095.1

OpenTargets

ENSG00000163041

Ensembl

ENSSSCT00000018727, ENSSSCT00000098149, ENSSSCG00000017202, ENSSSCP00000018225, ENSSSCG00000023971, ENSSSCP00000077047