Reactome | TCF7L1 [nucleoplasm]

TCF7L1 [nucleoplasm]

Stable Identifier

R-SSC-5228649

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

TCF7L1, A0A5G2Q9J1

Locations in the PathwayBrowser

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Developmental Biology (Sus scrofa)

- MITF-M-regulated melanocyte development (Sus scrofa)
  - MITF-M-dependent gene expression (Sus scrofa)
    - Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Sus scrofa)
      - HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Sus scrofa)
        
        HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Sus scrofa)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Sus scrofa)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Sus scrofa)
        
        TCF/LEF [nucleoplasm] (Sus scrofa)
        
        TCF7L1 [nucleoplasm] (Sus scrofa)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Sus scrofa)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Sus scrofa)
        
        TCF/LEF [nucleoplasm] (Sus scrofa)
        
        TCF7L1 [nucleoplasm] (Sus scrofa)

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - Transcriptional regulation by RUNX3 (Sus scrofa)
      - RUNX3 regulates WNT signaling (Sus scrofa)
        
        RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Sus scrofa)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Sus scrofa)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Sus scrofa)
        
        TCF7L1 [nucleoplasm] (Sus scrofa)
        
        RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Sus scrofa)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Sus scrofa)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Sus scrofa)
        
        TCF7L1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A5G2Q9J1

Gene Names

TCF7L1

Reference Genes

ENSEMBL:ENSSSCG00000008241.5

UCSC:A0A5G2Q9J1 TCF7L1

Other Identifiers

100523899

GO:0000785

GO:0000978

GO:0000981

GO:0003677

GO:0005634

GO:0006351

GO:0006355

GO:0006357

GO:0016055

GO:0023052

GO:0043226

GO:0060070

GO:0140110

GO:1990907

Ssc.25002.1.S1_at

Participates

as a candidate of

as a member of

TCF/LEF [nucleoplasm] (Sus scrofa)

Inferred From

TCF7L1 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCT00000086281, ENSSSCP00000059978, ENSSSCG00000008241

VGNC

93824