Reactome | MAPK10 [cytosol]

MAPK10 [cytosol]

Stable Identifier

R-SSC-450352

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

MAPK10, A0A8W4FNK5

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Cytokine Signaling in Immune system (Sus scrofa)
  - Signaling by Interleukins (Sus scrofa)
    - Interleukin-17 signaling (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
- Innate Immune System (Sus scrofa)
  - Fc epsilon receptor (FCERI) signaling (Sus scrofa)
    - FCERI mediated MAPK activation (Sus scrofa)
      - Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
  - Toll-like Receptor Cascades (Sus scrofa)
    - Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
    - Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
      - Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
      - Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
    - Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
      - MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
    - Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
      - MyD88-independent TLR4 cascade (Sus scrofa)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
    - Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
      - MyD88 cascade initiated on plasma membrane (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)
    - Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
      - MyD88 dependent cascade initiated on endosome (Sus scrofa)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
        
        MAP kinase activation (Sus scrofa)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
        
        MAPK8,9,10 [cytosol] (Sus scrofa)
        
        MAPK10 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A8W4FNK5

Gene Names

MAPK10

Reference Genes

ENSEMBL:ENSSSCG00000009228.6

UCSC:A0A8W4FNK5 MAPK10

Other Identifiers

GO:0000165

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0004705

GO:0004707

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0006468

GO:0007254

GO:0016301

GO:0016740

GO:0048511

GO:0106310

GO:0140096

Participates

as a member of

MAPK8,9,10 [cytosol] (Sus scrofa)

Other forms of this molecule

phospho-MAPK10 [cytosol]

phospho-MAPK10 [nucleoplasm]

Inferred From

MAPK10 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCG00000009228, ENSSSCP00000079880, ENSSSCT00000105393

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