Reactome | LAMA3 [extracellular region]

LAMA3 [extracellular region]

Stable Identifier

R-SSC-445991

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

LAMA3, F1SBB3

Locations in the PathwayBrowser

Expand all

Cell-Cell communication (Sus scrofa)

- Cell junction organization (Sus scrofa)
  - Type I hemidesmosome assembly (Sus scrofa)
    - BP230 interacts with keretin K5/K14 (Sus scrofa)
      - CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] (Sus scrofa)
        
        BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Sus scrofa)
        
        Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
      - Type II hemidesmosome [plasma membrane] (Sus scrofa)
        
        CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] (Sus scrofa)
        
        BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Sus scrofa)
        
        Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
    - BP230 is recruited to the hemidesmosome (Sus scrofa)
      - BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Sus scrofa)
        
        Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
      - Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
    - CD151 interacts with BP180 and the integrin alpha 6 subunit (Sus scrofa)
      - BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Sus scrofa)
        
        Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
      - CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] (Sus scrofa)
        
        BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Sus scrofa)
        
        Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)

Extracellular matrix organization (Sus scrofa)

- Collagen formation (Sus scrofa)
  - Assembly of collagen fibrils and other multimeric structures (Sus scrofa)
    - Hemidesmosome formation (Sus scrofa)
      - Collagen type VII fibril:Laminin-332 [extracellular region] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
      - Type I hemidesmosome complex [extracellular region] (Sus scrofa)
        
        Collagen type VII fibril:Laminin-332 [extracellular region] (Sus scrofa)
        
        Laminin-332 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
- Laminin interactions (Sus scrofa)
  - Laminins:Nidogens binds collagen type IV networks (Sus scrofa)
    - Laminins with gamma-1, gamma-3:Nidogens 1,2 [extracellular region] (Sus scrofa)
      - Laminins with gamma-1, gamma-3 [extracellular region] (Sus scrofa)
        
        Laminin-311 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
        
        Laminin-321 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
    - Laminins with gamma-1, gamma-3:Nidogens:Collagen type IV network [extracellular region] (Sus scrofa)
      - Laminins with gamma-1, gamma-3:Nidogens 1,2 [extracellular region] (Sus scrofa)
        
        Laminins with gamma-1, gamma-3 [extracellular region] (Sus scrofa)
        
        Laminin-311 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)
        
        Laminin-321 [extracellular region] (Sus scrofa)
        
        LAMA3 [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SBB3

Gene Names

LAMA3

Reference Genes

ENSEMBL:ENSSSCG00000003709.5

Other Identifiers

100511642

GO:0005102

GO:0005576

GO:0005604

GO:0005610

GO:0005783

GO:0007155

GO:0016020

GO:0030154

GO:0030155

GO:0030312

GO:0030334

GO:0031012

GO:0035987

GO:0043226

GO:0045995

GO:0048856

GO:0048870

Ssc.2444.2.A1_a_at

Participates

as a component of

Inferred From

LAMA3 [extracellular region] (Homo sapiens)

Cross References

OpenTargets

ENSG00000053747

Ensembl

ENSSSCT00000004108, ENSSSCG00000003709, ENSSSCP00000004016

VGNC

98490

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