Reactome | NPFFR2 [plasma membrane]

NPFFR2 [plasma membrane]

Stable Identifier

R-SSC-389476

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

NPFFR2, F1RUN6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)
      - The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
        
        GPCRs that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Orexin and neuropeptides FF and QRFP bind to their respective receptors (Sus scrofa)
        
        Two NPFF receptors can bind neuropeptide FF (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)
        
        NPFFR2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RUN6

Gene Names

NPFFR2

Reference Genes

ENSEMBL:ENSSSCG00000008944.5

Other Identifiers

100524634

GO:0004930

GO:0005856

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008188

GO:0015629

GO:0016020

GO:0023052

GO:0031628

GO:0032870

GO:0036211

GO:0042277

GO:0043226

GO:0043408

GO:0045761

GO:0060089

GO:2000479

Participates

as a member of

NPFFR1,NPFFR2 [plasma membrane] (Sus scrofa)

Inferred From

NPFFR2 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000056291

Ensembl

ENSSSCT00000009798, ENSSSCP00000009545, ENSSSCG00000008944

VGNC

90847