Reactome | NPFF [extracellular region]

NPFF [extracellular region]

Stable Identifier

R-SSC-389415

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

NPFF(69-76), A0A4X1WAK1

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR downstream signalling (Sus scrofa)
    - G alpha (q) signalling events (Sus scrofa)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFF [extracellular region] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFF [extracellular region] (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Orexin and neuropeptides FF and QRFP bind to their respective receptors (Sus scrofa)
        
        Two NPFF receptors can bind neuropeptide FF (Sus scrofa)
        
        NPFF [extracellular region] (Sus scrofa)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)
        
        NPFF [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A4X1WAK1

Gene Names

NPFF

Reference Genes

ENSEMBL:ENSSSCG00000000277.5

UCSC:A0A4X1WAK1 NPFF

Other Identifiers

100518250

GO:0001664

GO:0005102

GO:0005184

GO:0005615

GO:0007218

GO:0030425

GO:0043204

GO:0043679

GO:0048018

GO:0060079

GO:0098772

GO:0098794

GO:0160041

Participates

as an input of

Two NPFF receptors can bind neuropeptide FF (Sus scrofa)

as a component of

NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Sus scrofa)

Inferred From

NPFF(69-76) [extracellular region] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCP00000000293, ENSSSCT00000000298, ENSSSCG00000000277

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