Reactome | DLG1 [plasma membrane]

DLG1 [plasma membrane]

Stable Identifier

R-SSC-375977

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

DLG1, A0A287BTJ2

Locations in the PathwayBrowser

Expand all

Neuronal System (Sus scrofa)

- Protein-protein interactions at synapses (Sus scrofa)
  - Synaptic adhesion-like molecules (Sus scrofa)
    - SALMs 1-3 bind to PSD-95 family members (Sus scrofa)
      - PSD-95 family [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)
      - SALMs 1-3:PSD-95 family [plasma membrane] (Sus scrofa)
        
        PSD-95 family [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)
- Transmission across Chemical Synapses (Sus scrofa)
  - Neurotransmitter receptors and postsynaptic signal transmission (Sus scrofa)
    - Activation of NMDA receptors and postsynaptic events (Sus scrofa)
      - Unblocking of NMDA receptors, glutamate binding and activation (Sus scrofa)
        
        Ca2+ influx into the post-synaptic cell (Sus scrofa)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Sus scrofa)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Sus scrofa)
        
        DLG1 homotetramer [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)
        
        Membrane depolarization upon activation of Ca impermeable AMPA receptors (Sus scrofa)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Sus scrofa)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Sus scrofa)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Sus scrofa)
        
        DLG1 homotetramer [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)
    - Activation of kainate receptors upon glutamate binding (Sus scrofa)
      - Ionotropic activity of kainate receptors (Sus scrofa)
        
        Activation of Ca-permeable Kainate Receptor (Sus scrofa)
        
        Activation of Ca-permeable Kainate receptors (Sus scrofa)
        
        Kainate receptor-glutamate complex [plasma membrane] (Sus scrofa)
        
        Kainate Receptors [plasma membrane] (Sus scrofa)
        
        GRIK 2 homomer [plasma membrane] (Sus scrofa)
        
        GRIK2 interacting proteins [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)
        
        kainate receptor binds glutamate (Sus scrofa)
        
        Kainate Receptors [plasma membrane] (Sus scrofa)
        
        GRIK 2 homomer [plasma membrane] (Sus scrofa)
        
        GRIK2 interacting proteins [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)
        
        Kainate receptor-glutamate complex [plasma membrane] (Sus scrofa)
        
        Kainate Receptors [plasma membrane] (Sus scrofa)
        
        GRIK 2 homomer [plasma membrane] (Sus scrofa)
        
        GRIK2 interacting proteins [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)
    - Glutamate binding, activation of AMPA receptors and synaptic plasticity (Sus scrofa)
      - Trafficking of AMPA receptors (Sus scrofa)
        
        Trafficking of GluR1-containing AMPA receptors (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)

Signal Transduction (Sus scrofa)

- MAPK family signaling cascades (Sus scrofa)
  - MAPK1/MAPK3 signaling (Sus scrofa)
    - RAF/MAP kinase cascade (Sus scrofa)
      - RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
        
        RAS GEFs [plasma membrane] (Sus scrofa)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Sus scrofa)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Sus scrofa)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Sus scrofa)
        
        DLG1 homotetramer [plasma membrane] (Sus scrofa)
        
        DLG1 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287BTJ2

Gene Names

DLG1

Reference Genes

BioGPS Gene:100157729 DLG1

ENSEMBL:ENSSSCG00000011833.6

Monarch:100157729 DLG1

NCBI Gene:100157729 DLG1

UCSC:A0A287BTJ2 DLG1

Reference Transcript

RefSeq:XM_021070100.1 DLG1

Other Identifiers

100157729

GO:0000122

GO:0001657

GO:0001658

GO:0001771

GO:0001772

GO:0001935

GO:0002088

GO:0002376

GO:0003012

GO:0005198

GO:0005515

GO:0005604

GO:0005634

GO:0005737

GO:0005783

GO:0005789

GO:0005794

GO:0005874

GO:0005886

GO:0005911

GO:0005923

GO:0006355

GO:0007010

GO:0007015

GO:0007163

GO:0007268

GO:0007399

GO:0008104

GO:0008283

GO:0008284

GO:0008360

GO:0009898

GO:0014069

GO:0015459

GO:0016020

GO:0016323

GO:0016324

GO:0016328

GO:0019900

GO:0019901

GO:0019902

GO:0030041

GO:0030054

GO:0030312

GO:0030432

GO:0030838

GO:0030866

GO:0030953

GO:0031012

GO:0031253

GO:0031503

GO:0031579

GO:0031594

GO:0031641

GO:0033268

GO:0034330

GO:0035255

GO:0035418

GO:0035748

GO:0042098

GO:0042110

GO:0042130

GO:0042391

GO:0042982

GO:0043005

GO:0043113

GO:0043219

GO:0043226

GO:0043268

GO:0043491

GO:0043622

GO:0044325

GO:0045121

GO:0045197

GO:0045202

GO:0048471

GO:0048608

GO:0048704

GO:0048729

GO:0048745

GO:0048856

GO:0050680

GO:0051660

GO:0051898

GO:0060022

GO:0060090

GO:0061024

GO:0070161

GO:0070373

GO:0070830

GO:0072659

GO:0097016

GO:0097025

GO:0097060

GO:0097120

GO:0098609

GO:0098772

GO:0098839

GO:0098911

GO:0098915

GO:0098919

GO:0098978

GO:0099072

GO:0099562

GO:0099645

GO:1902473

GO:1903078

GO:1903286

GO:1903753

GO:1903764

GO:2000134

Ssc.2426.1.S1_at

Ssc.27547.1.A1_at

Participates

as a component of

as a member of

PSD-95 family [plasma membrane] (Sus scrofa)

as an output of

Trafficking of GluR1-containing AMPA receptors (Sus scrofa)

Other forms of this molecule

DLG1 [cytosol]

Inferred From

DLG1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_020925759.1

ENSEMBL

ENSSSCG00000011833, ENSSSCP00000059551, ENSSSCT00000055575

VGNC

87326

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