Reactome | DSG2 [plasma membrane]

DSG2 [plasma membrane]

Stable Identifier

R-SSC-351896

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

DSG2, A0A287ATF2

Locations in the PathwayBrowser

Expand all

Developmental Biology (Sus scrofa)

- Keratinization (Sus scrofa)
  - Formation of the cornified envelope (Sus scrofa)
    - Fillagrin and keratin intermediate filaments polymerize forming a network (Sus scrofa)
      - FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG2 [plasma membrane] (Sus scrofa)
      - FLG-Keratin filament network [plasma membrane] (Sus scrofa)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG2 [plasma membrane] (Sus scrofa)
    - PERP binds desmosomes (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG2 [plasma membrane] (Sus scrofa)
      - Desmosome:PERP [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG2 [plasma membrane] (Sus scrofa)
    - Plasma membrane resorption (Sus scrofa)
      - Mature cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-cornified envelope:CDSN [plasma membrane] (Sus scrofa)
        
        No FGN-Cornified envelope [plasma membrane] (Sus scrofa)
        
        No FGN-late cornified envelope [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome network [plasma membrane] (Sus scrofa)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
        
        Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG2 [plasma membrane] (Sus scrofa)
  - Keratin filaments bind cell-cell adhesion complexes (Sus scrofa)
    - Desmosome [plasma membrane] (Sus scrofa)
      - Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG2 [plasma membrane] (Sus scrofa)
    - Keratin tonofilament:Desmosome [plasma membrane] (Sus scrofa)
      - Desmosome [plasma membrane] (Sus scrofa)
        
        Desmogelins [plasma membrane] (Sus scrofa)
        
        DSG2 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287ATF2

Gene Names

DSG2

Reference Genes

ENSEMBL:ENSSSCG00000022739.4

Other Identifiers

100625833

GO:0002934

GO:0003012

GO:0003013

GO:0003165

GO:0005509

GO:0005886

GO:0007155

GO:0007156

GO:0014704

GO:0016020

GO:0030054

GO:0030057

GO:0034330

GO:0043226

GO:0043231

GO:0048856

GO:0050839

GO:0070161

GO:0086073

GO:0086091

GO:0098609

GO:0098911

Ssc.3584.1.S1_at

Ssc.3584.2.S1_at

Ssc.3584.3.S1_at

Participates

as a candidate of

as a member of

Desmogelins [plasma membrane] (Sus scrofa)

as an input of

Caspase-mediated cleavage of Desmoglein 2 (Sus scrofa)

Other forms of this molecule

DSG2 [cornified envelope]

DSG2 [plasma membrane]

Inferred From

DSG2 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000046604

Ensembl

ENSSSCT00000051217, ENSSSCG00000022739, ENSSSCP00000047363

VGNC

87456