Reactome | MTA1 [nucleoplasm]

MTA1 [nucleoplasm]

Stable Identifier

R-SSC-3465550

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

MTA1, A0A286ZS52

Locations in the PathwayBrowser

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Chromatin organization (Sus scrofa)

- ATP-dependent chromatin remodelers (Sus scrofa)
  - CHD chromatin remodelers (Sus scrofa)
    - CHD3, CHD4, CHD5 subfamily (Sus scrofa)
      - NuRD complex assembly (Sus scrofa)
        
        CHD and CDK2AP subunits are recruited to NuRD (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        HDAC1, 2 bind MTA1, 2, 3 and RBBP4,7 (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        Interaction of NuRD complexes with transcription factors (Sus scrofa)
        
        GATAD2A NuRD binds ZMYND8:ZNF532:ZNF592:ZNF687 (Sus scrofa)
        
        GATAD2A NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4, RBBP7:MBD2,MBD3:GATAD2A [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        ZMYND8:ZNF532:ZNF592:ZNF687:GATAD2A NuRD [nucleoplasm] (Sus scrofa)
        
        GATAD2A NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4, RBBP7:MBD2,MBD3:GATAD2A [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD binds Ikaros family member proteins (Sus scrofa)
        
        IKZF1,IKZF2,IKZF3:NuRD [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD binds TCF19 at FBP1 gene (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        TCF19:NuRD:FBP1 gene:H3K4 nucleosome [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD binds TCF19 at G6PC gene (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        TCF19:NuRD:G6PC gene:H3K4 nucleosome [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD binds TCF19 at PCK1 gene (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        TCF19:NuRD:PCK1 gene:H3K4 nucleosome [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD deacetylates telomeric nucleosomes (Sus scrofa)
        
        NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NR2C2,NR2F2:ZNF827:NuRD:telomeric chromatin [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        PHF6 binds NuRD (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        PHF6:NuRD [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        ZNF827 and NR2C2,NR2F2 recruit NuRD to telomeric chromatin (Sus scrofa)
        
        NR2C2,NR2F2:ZNF827:NuRD:H4K5,H4K8 Ac telomeric chromatin [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        NuRD [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        MBD2, MBD3 and GATAD2A, GATAD2B bind core NuRD complex (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        MBD3L2 binds MBD3 NuRD core complex (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        MBD3L2:HDAC1,HDAC2:MTA1,MTA2,MTA3:RBBP4,RBBP7:MBD3:GATAD2A,GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm] (Sus scrofa)
        
        HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4,RBBP7 [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
- Chromatin modifying enzymes (Sus scrofa)
  - HDACs deacetylate histones (Sus scrofa)
    - HDAC1:2-containing complex binds HDAC2 Inhibitors (Sus scrofa)
      - HDAC1:2-containing complex [nucleoplasm] (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
      - HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Sus scrofa)
        
        HDAC1:2-containing complex [nucleoplasm] (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase I Transcription (Sus scrofa)
  - RNA Polymerase I Promoter Clearance (Sus scrofa)
    - RNA Polymerase I Transcription Initiation (Sus scrofa)
      - Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Sus scrofa)
        
        TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Intracellular signaling by second messengers (Sus scrofa)
  - PIP3 activates AKT signaling (Sus scrofa)
    - PTEN Regulation (Sus scrofa)
      - Regulation of PTEN gene transcription (Sus scrofa)
        
        SALL4 recruits NuRD to PTEN gene (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)
        
        SALL4:NuRD:PTEN gene [nucleoplasm] (Sus scrofa)
        
        SALL4:NuRD [nucleoplasm] (Sus scrofa)
        
        NuRD complex [nucleoplasm] (Sus scrofa)
        
        MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)
        
        MTA1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZS52

Gene Names

MTA1

Reference Genes

BioGPS Gene:110258362 MTA1

ENSEMBL:ENSSSCG00000032544.3

Monarch:110258362 MTA1

NCBI Gene:110258362 MTA1

UCSC:A0A286ZS52 MTA1

Reference Transcript

RefSeq:XM_021081638.1 MTA1

Other Identifiers

110258362

GO:0000122

GO:0000978

GO:0003677

GO:0003682

GO:0003713

GO:0003714

GO:0005634

GO:0005635

GO:0005654

GO:0005737

GO:0005829

GO:0005874

GO:0006281

GO:0006302

GO:0006325

GO:0006338

GO:0006355

GO:0008270

GO:0010212

GO:0016581

GO:0030163

GO:0042826

GO:0043161

GO:0043565

GO:0045814

GO:0045893

GO:0046872

GO:0061629

GO:1902499

Ssc.12049.1.A1_at

Ssc.27323.1.A1_at

Participates

as an input of

PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Sus scrofa)

as a member of

MTA1, MTA2, MTA3 [nucleoplasm] (Sus scrofa)

Other forms of this molecule

MTA1 [nucleoplasm]

Inferred From

MTA1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020937297.1

ENSEMBL

ENSSSCT00000039197, ENSSSCG00000032544, ENSSSCP00000034479

VGNC

90434

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