Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
STING1 [cytoplasmic vesicle membrane]
Stable Identifier
R-SSC-3248021
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytoplasmic vesicle membrane
Synonyms
K63polyUb-STING, F1RGH2
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Cytosolic sensors of pathogen-associated DNA (Sus scrofa)
Regulation of innate immune responses to cytosolic DNA (Sus scrofa)
DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Sus scrofa)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172,K48polyUb-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Sus scrofa)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING mediated induction of host immune responses (Sus scrofa)
IRF3-mediated induction of type I IFN (Sus scrofa)
IRF3 is phosphorylated by TBK1 (Sus scrofa)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Sus scrofa)
STING:TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STAT6-mediated induction of chemokines (Sus scrofa)
STING recruits TBK1 and STAT6 (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:TBK1:STAT6 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Sus scrofa)
STING:TBK1:STAT6 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
TBK1 phosphorylates STAT6 at Ser407 (Sus scrofa)
STING:p-S172-TBK1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:p-S172-TBK1:STAT6 [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING binds c-di-GMP (Sus scrofa)
STING:c-di-GMP [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
STING binds cyclic GMP-AMP (Sus scrofa)
STING:cGAMP [cytoplasmic vesicle membrane] (Sus scrofa)
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
STING1 [cytoplasmic vesicle membrane] (Sus scrofa)
External Reference Information
External Reference
UniProt:F1RGH2
Gene Names
STING1
Reference Genes
ENSEMBL:ENSSSCG00000014349.6
UCSC:F1RGH2 STING1
Other Identifiers
100217389
GO:0000045
GO:0000139
GO:0000166
GO:0000421
GO:0002218
GO:0002221
GO:0002230
GO:0002376
GO:0002753
GO:0003713
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005768
GO:0005773
GO:0005776
GO:0005777
GO:0005783
GO:0005789
GO:0005794
GO:0005815
GO:0005829
GO:0005929
GO:0006355
GO:0006811
GO:0006886
GO:0010468
GO:0015252
GO:0016020
GO:0016239
GO:0019901
GO:0031625
GO:0032481
GO:0032527
GO:0032728
GO:0033116
GO:0034220
GO:0035438
GO:0035458
GO:0035591
GO:0036064
GO:0042802
GO:0042803
GO:0043226
GO:0045087
GO:0045944
GO:0048471
GO:0050727
GO:0051259
GO:0051607
GO:0055085
GO:0060090
GO:0060340
GO:0061507
GO:0061629
GO:0061709
GO:0065003
GO:0070972
GO:0071360
GO:0098542
GO:0120283
GO:0140374
GO:0140896
GO:0141111
GO:1902600
GO:1990231
Participates
as a component of
STING:STING [cytoplasmic vesicle membrane] (Sus scrofa)
Other forms of this molecule
STING1 [plasma membrane]
STING1 [secretory granule membrane]
STING1 [endoplasmic reticulum membrane]
STING1 [endoplasmic reticulum membrane]
Inferred From
K63polyUb-STING [cytoplasmic vesicle membrane]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 150 (in Homo sapiens)
Coordinate
150
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
ENSEMBL
ENSSSCT00000015677
,
ENSSSCP00000015264
,
ENSSSCG00000014349
VGNC
93547
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text