Reactome | ZNF74 [nucleoplasm]

ZNF74 [nucleoplasm]

Stable Identifier

R-SSC-3110227-2

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

ZNF778, A0A287B0B3

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- Epigenetic regulation of gene expression (Sus scrofa)
  - Regulation of endogenous retroelements (Sus scrofa)
    - Regulation of endogenous retroelements by KRAB-ZFP proteins (Sus scrofa)
      - ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Sus scrofa)
        
        ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
        
        SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
      - CBX5 (HP-1alpha) binds TRIM28 (KAP1) in SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Sus scrofa)
        
        CBX5:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement [nucleoplasm] (Sus scrofa)
        
        SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
        
        SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
      - KRAB-ZFP binds retroelement DNA in chromatin (Sus scrofa)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
      - SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Sus scrofa)
        
        ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFP:retroelement chromatin [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
        
        ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFP:retroelement chromatin with H3K9me3 [nucleoplasm] (Sus scrofa)
        
        KRAB-ZFPs that bind, repress retroelements [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - KRAB-ZNF / KAP Interaction (Sus scrofa)
      - KRAB-ZNF / KAP Complex [nucleoplasm] (Sus scrofa)
        
        KRAB-ZNF [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)
      - KRAB-ZNF [nucleoplasm] (Sus scrofa)
        
        Homologues of ZNF778 [nucleoplasm] (Sus scrofa)
        
        ZNF74 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287B0B3

Gene Names

ZNF74

Reference Genes

ENSEMBL:ENSSSCG00000060069.1

UCSC:A0A287B0B3 ZNF74

Other Identifiers

100626009

GO:0000977

GO:0000981

GO:0003677

GO:0005634

GO:0005654

GO:0005856

GO:0006355

GO:0006357

GO:0008270

GO:0015629

GO:0031981

GO:0046872

Ssc.23008.1.S1_at

Participates

as a member of

Homologues of ZNF778 [nucleoplasm] (Sus scrofa)

Other forms of this molecule

ZNF74 [nucleoplasm]

Inferred From

ZNF778 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCT00000045835, ENSSSCP00000049857, ENSSSCG00000060069