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ITSN1 [cytosol]
Stable Identifier
R-SSC-3006481
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
ITSN1, A0A5G2QFN5
Locations in the PathwayBrowser
Expand all
Developmental Biology (Sus scrofa)
Nervous system development (Sus scrofa)
Axon guidance (Sus scrofa)
EPH-Ephrin signaling (Sus scrofa)
EPHB-mediated forward signaling (Sus scrofa)
CDC42 and PIP2 bind WASL, activating it (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Sus scrofa)
ITSN1:N-WASP [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Sus scrofa)
ITSN1:N-WASP [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
N-WASP binds ARP2/3 and G-actin (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Sus scrofa)
ITSN1:N-WASP [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Sus scrofa)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Sus scrofa)
ITSN1:N-WASP [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Death Receptor Signaling (Sus scrofa)
p75 NTR receptor-mediated signalling (Sus scrofa)
Cell death signalling via NRAGE, NRIF and NADE (Sus scrofa)
NRAGE signals death through JNK (Sus scrofa)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Sus scrofa)
GEFs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (12/13) signalling events (Sus scrofa)
GEFs activate RhoA,B,C (Sus scrofa)
GEFs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase cycle (Sus scrofa)
CDC42 GTPase cycle (Sus scrofa)
CDC42 GEFs activate CDC42 (Sus scrofa)
CDC42 GEFs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
RHOG GTPase cycle (Sus scrofa)
RHOG GEFs activate RHOG (Sus scrofa)
RHOG GEFs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
RHOQ GTPase cycle (Sus scrofa)
RHOQ GEFs activate RHOQ (Sus scrofa)
RHOQ GEFs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Vesicle-mediated transport (Sus scrofa)
Membrane Trafficking (Sus scrofa)
Clathrin-mediated endocytosis (Sus scrofa)
AAK1 phosphorylates AP-2 mu subunit at T156 (Sus scrofa)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
BAR domain proteins recruit dynamin (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Cargo recognition for clathrin-mediated endocytosis (Sus scrofa)
ARBB recruits GPCRs into clathrin-coated pits (Sus scrofa)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Clathrin recruits PIK3C2A (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Endophilins recruit synaptojanins to the clathrin-coated pit (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
F- and N- BAR domain proteins bind the clathrin-coated pit (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
RAB5 and GAPVD1 bind AP-2 (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
Recruitment of AP-2 complex and clathrin (Sus scrofa)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
SNX9 recruits components of the actin polymerizing machinery (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Sus scrofa)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
ITSNs [cytosol] (Sus scrofa)
ITSN1 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5G2QFN5
Gene Names
ITSN1
Reference Genes
ENSEMBL:ENSSSCG00000024614.4
Other Identifiers
100737549
GO:0005886
GO:0005905
GO:0008104
GO:0060090
GO:0070064
Participates
as a member of
ITSNs [cytosol] (Sus scrofa)
RHOG GEFs [cytosol] (Sus scrofa)
RHOQ GEFs [cytosol] (Sus scrofa)
GEFs [cytosol] (Sus scrofa)
as a candidate of
CDC42 GEFs [cytosol] (Sus scrofa)
as a component of
ITSN1:N-WASP [cytosol] (Sus scrofa)
Inferred From
ITSN1 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000205726
Ensembl
ENSSSCT00000078428
,
ENSSSCP00000063036
,
ENSSSCG00000024614
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