Reactome | RAD51C [nucleoplasm]

RAD51C [nucleoplasm]

Stable Identifier

R-SSC-217039

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

RAD51C, A0A8D0PFN3

Locations in the PathwayBrowser

Expand all

DNA Repair (Sus scrofa)

- DNA Double-Strand Break Repair (Sus scrofa)
  - Homology Directed Repair (Sus scrofa)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
      - HDR through Homologous Recombination (HRR) (Sus scrofa)
        
        D-loop extension by DNA polymerases (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Homologous DNA Pairing and Strand Exchange (Sus scrofa)
        
        CX3 complex binds D-loop structures (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        CX3 complex formation (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        D-loop formation mediated by PALB2, BRCA2 and RAD51 (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Presynaptic phase of homologous DNA pairing and strand exchange (Sus scrofa)
        
        BCDX2 complex formation (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex stabilizes RAD51 filament (Sus scrofa)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Resolution of D-Loop Structures (Sus scrofa)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Sus scrofa)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Sus scrofa)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        FIGNL1 binds RAD51 (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:FIRRM:FIGNL1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        MUS81:EME1,EME2 cleaves D-loop (Sus scrofa)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Sus scrofa)
        
        CX3 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Sus scrofa)
        
        BCDX2 complex [nucleoplasm] (Sus scrofa)
        
        RAD51C [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A8D0PFN3

Gene Names

RAD51C

Reference Genes

BioGPS Gene:100518577 RAD51C

ENSEMBL:ENSSSCG00005037306.1

Monarch:100518577 RAD51C

NCBI Gene:100518577 RAD51C

UCSC:A0A8D0PFN3 RAD51C

Reference Transcript

RefSeq:XM_021067279.1 RAD51C

Other Identifiers

100518577

GO:0000166

GO:0000400

GO:0000707

GO:0000722

GO:0000724

GO:0003677

GO:0005524

GO:0005634

GO:0005654

GO:0005657

GO:0005737

GO:0005739

GO:0005829

GO:0006281

GO:0006310

GO:0006974

GO:0007066

GO:0007131

GO:0007141

GO:0007283

GO:0008821

GO:0010971

GO:0022414

GO:0030054

GO:0032200

GO:0033063

GO:0033065

GO:0048471

GO:0065003

GO:0140013

GO:0140664

Participates

as an input of

as a component of

Inferred From

RAD51C [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020922938.1

ENSEMBL

ENSSSCT00000023145, ENSSSCG00000023955, ENSSSCP00000024519

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