Reactome | COL7A1 [endoplasmic reticulum lumen]

COL7A1 [endoplasmic reticulum lumen]

Stable Identifier

R-SSC-2023565

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

endoplasmic reticulum lumen

Synonyms

3x4Hyp-3Hyp-GalHyl-COL7A1, F1SKM1

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPII-mediated vesicle transport (Sus scrofa)
        
        Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        Loss of SAR1B GTPase (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        Cargo concentration in the ER (Sus scrofa)
        
        Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        MIA2 and MIA3 dissociate from procollagen VII vesicle (Sus scrofa)
        
        procollagen VII:MIA3:MIA2:PREB:SEC23A:SEC24C [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        MIA2 and MIA3 load procollagen VII into COPII vesicles (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        procollagen VII:MIA3:MIA2:PREB:SEC23A:SEC24C [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        MIA3 binds procollagen VII (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPII-mediated vesicle transport (Sus scrofa)
      - Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
      - Loss of SAR1B GTPase (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
      - Vesicle budding (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
    - Cargo concentration in the ER (Sus scrofa)
      - Inner coat assembly and cargo binding (Sus scrofa)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
      - MIA2 and MIA3 dissociate from procollagen VII vesicle (Sus scrofa)
        
        procollagen VII:MIA3:MIA2:PREB:SEC23A:SEC24C [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        procollagen VII:SEC24C:SEC23A [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
      - MIA2 and MIA3 load procollagen VII into COPII vesicles (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        procollagen VII:MIA3:MIA2:PREB:SEC23A:SEC24C [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
      - MIA3 binds procollagen VII (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)
        
        Procollagen type VII:MIA3 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)
        
        COL7A1 [endoplasmic reticulum lumen] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SKM1

Gene Names

COL7A1

Reference Genes

BioGPS Gene:100523209 COL7A1

ENSEMBL:ENSSSCG00000011355.5

KEGG:ssc:100523209 COL7A1

Monarch:100523209 COL7A1

NCBI Gene:100523209 COL7A1

UCSC:F1SKM1 COL7A1

Reference Transcript

Other Identifiers

100523209

GO:0004867

GO:0005198

GO:0005515

GO:0005576

GO:0005581

GO:0005604

GO:0007155

GO:0030020

GO:0030312

GO:0030414

GO:0031012

GO:0042802

GO:0098772

Participates

as an input of

Association of procollagen type VII (Sus scrofa)

as a component of

Procollagen type VII [endoplasmic reticulum lumen] (Sus scrofa)

Other forms of this molecule

COL7A1 [extracellular region]

COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

COL7A1 [extracellular region]

COL7A1 [endoplasmic reticulum lumen]

COL7A1 [COPII-coated ER to Golgi transport vesicle]

COL7A1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred From

Alpha-1(VII) chains [endoplasmic reticulum lumen] (Homo sapiens)

3x4Hyp-3Hyp-GalHyl-COL7A1 [endoplasmic reticulum lumen] (Homo sapiens)

Modified Residues

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,3S)-3-hydroxyproline at unknown position

PsiMod Name

(2S,3S)-3-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.

Name

O5-galactosyl-L-hydroxylysine at unknown position

PsiMod Name

O5-galactosyl-L-hydroxylysine

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.

Cross References

RefSeq

XP_013837111.1, XP_005669576.1

ENSEMBL

ENSSSCT00000012432, ENSSSCG00000011355, ENSSSCP00000012108

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