Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
YWHAE dimer [cytosol]
Stable Identifier
R-SSC-194364
Type
Complex
Species
Sus scrofa
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
G2/M DNA damage checkpoint (Sus scrofa)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Sus scrofa)
Association of p-S216-CDC25C with 14-3-3 proteins (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to heat stress (Sus scrofa)
HSF1 activation (Sus scrofa)
HSF1 trimer translocates to the nucleus (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Regulation of HSF1-mediated heat shock response (Sus scrofa)
p-S303,307-HSF1 binds YWHAE (14-3-3) (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
p-S303,307-HSF1:YWHAE [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
DDIT4 binds 14-3-3 dimer (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
DDIT4:14-3-3 dimer [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
DDIT4:14-3-3 dimer [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Intrinsic Pathway for Apoptosis (Sus scrofa)
Activation of BH3-only proteins (Sus scrofa)
Activation of BAD and translocation to mitochondria (Sus scrofa)
Activation of BAD by calcineurin (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Sequestration of BAD protein by 14-3-3 (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Death Receptor Signaling (Sus scrofa)
p75 NTR receptor-mediated signalling (Sus scrofa)
Cell death signalling via NRAGE, NRIF and NADE (Sus scrofa)
NADE modulates death signalling (Sus scrofa)
14-3-3epsilon attentuates NADE-related apoptosis (Sus scrofa)
NGF ligand:p75NTR:NADE:14-3-3epsilon [plasma membrane] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Signaling by Hippo (Sus scrofa)
YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
p-WWTR1:YWHAE [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases activate PKNs (Sus scrofa)
Association of p-S216-CDC25C with 14-3-3 proteins (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Sus scrofa)
14-3-3 dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
Vesicle-mediated transport (Sus scrofa)
Membrane Trafficking (Sus scrofa)
Rab regulation of trafficking (Sus scrofa)
RAB GEFs exchange GTP for GDP on RABs (Sus scrofa)
DENND1s exchange GTP for GDP on RAB35 (Sus scrofa)
RAB35 GEFs [cytosol] (Sus scrofa)
p-2S-DENND1A,B:YWHAE dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
YWHAE dimer binds phosphorylated DENND1 proteins (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
p-2S-DENND1A,B:YWHAE dimer [cytosol] (Sus scrofa)
YWHAE dimer [cytosol] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
YWHAE [cytosol]
(Sus scrofa)
Participates
as an input of
YWHAE dimer binds phosphorylated DENND1 proteins (Sus scrofa)
p-S303,307-HSF1 binds YWHAE (14-3-3) (Sus scrofa)
14-3-3epsilon attentuates NADE-related apoptosis (Sus scrofa)
YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Sus scrofa)
as a component of
p-2S-DENND1A,B:YWHAE dimer [cytosol] (Sus scrofa)
p-S303,307-HSF1:YWHAE [cytosol] (Sus scrofa)
NGF ligand:p75NTR:NADE:14-3-3epsilon [plasma membrane] (Sus scrofa)
p-WWTR1:YWHAE [cytosol] (Sus scrofa)
as a member of
14-3-3 dimer [cytosol] (Sus scrofa)
This entity regulates
Negatively
HSF1 trimer translocates to the nucleus
(Sus scrofa)
Inferred From
YWHAE dimer [cytosol]
(Homo sapiens)
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text