Reactome | ANAPC1 [nucleoplasm]

ANAPC1 [nucleoplasm]

Stable Identifier

R-SSC-174217

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

ANAPC1, A0A286ZW91

Locations in the PathwayBrowser

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Cell Cycle (Sus scrofa)

- Cell Cycle, Mitotic (Sus scrofa)
  - Regulation of mitotic cell cycle (Sus scrofa)
    - APC/C-mediated degradation of cell cycle proteins (Sus scrofa)
      - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Sus scrofa)
        
        APC/C:Cdh1 polyubiquitinates SKP2 (Sus scrofa)
        
        PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        APC/C:Cdh1-mediated degradation of Skp2 (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        RB1 recruits APC/C:Cdh1 complex to SKP2 (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
      - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Sus scrofa)
        
        Phosphorylation of the APC/C (Sus scrofa)
        
        Free APC/C phosphorylated by Cyclin B:Cdc2 (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Free APC/C phosphorylated by Plk1 (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
      - Autodegradation of Cdh1 by Cdh1:APC/C (Sus scrofa)
        
        Degradation of multiubiquitinated Cdh1 (Sus scrofa)
        
        multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Sus scrofa)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Multiubiquitination of APC/C-associated Cdh1 (Sus scrofa)
        
        multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Sus scrofa)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
      - Regulation of APC/C activators between G1/S and early anaphase (Sus scrofa)
        
        Association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Dissociation of phospho-Cdh1 from the APC/C complex (Sus scrofa)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Sus scrofa)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)

Cellular responses to stimuli (Sus scrofa)

- Cellular responses to stress (Sus scrofa)
  - Cellular Senescence (Sus scrofa)
    - Senescence-Associated Secretory Phenotype (SASP) (Sus scrofa)
      - CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
      - CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Sus scrofa)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
      - Cdh1:APC/C complex binds EHMT1:EHMT2 (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
      - Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Sus scrofa)
        
        EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)
        
        Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Sus scrofa)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)
        
        ANAPC1 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZW91

Gene Names

ANAPC1

Reference Genes

BioGPS Gene:100519830 ANAPC1

ENSEMBL:ENSSSCG00000008105.5

Monarch:100519830 ANAPC1

NCBI Gene:100519830 ANAPC1

UCSC:A0A286ZW91 ANAPC1

Reference Transcript

Other Identifiers

100519830

GO:0005634

GO:0005680

GO:0007091

GO:0030163

GO:0031145

GO:0051301

GO:0060090

GO:0070936

GO:0070979

GO:0141198

Ssc.22606.1.A1_at

Ssc.23851.1.A1_at

Participates

as a component of

phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Sus scrofa)

Other forms of this molecule

ANAPC1 [cytosol]

Inferred From

ANAPC1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_020942696.1, XP_020942695.1

ENSEMBL

ENSSSCG00000008105, ENSSSCT00000037279, ENSSSCP00000035765

VGNC

85293

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