Reactome | NDUFB2 [mitochondrial inner membrane]

NDUFB2 [mitochondrial inner membrane]

Stable Identifier

R-SSC-163941

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

mitochondrial inner membrane

Synonyms

NDUFB2, A0A4X1V766

Locations in the PathwayBrowser

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Metabolism (Sus scrofa)

- Aerobic respiration and respiratory electron transport (Sus scrofa)
  - Respiratory electron transport (Sus scrofa)
    - Complex I biogenesis (Sus scrofa)
      - Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
      - Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
      - The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
      - The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)
    - Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Sus scrofa)
      - Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFB2 [mitochondrial inner membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A4X1V766

Gene Names

NDUFB2

Reference Genes

BioGPS Gene:100513895 NDUFB2

ENSEMBL:ENSSSCG00005023979.1

KEGG:ssc:100513895 NDUFB2

Monarch:100513895 NDUFB2

NCBI Gene:100513895 NDUFB2

UCSC:A0A4X1V766 NDUFB2

Reference Transcript

RefSeq:NM_001244885.1 NDUFB2

Other Identifiers

100513895

GO:0005739

GO:0005743

GO:0016020

GO:0045271

Ssc.1311.1.A1_at

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Sus scrofa)

Inferred From

NDUFB2 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001231814.1

ENSEMBL

ENSSSCG00000032390, ENSSSCT00000059595, ENSSSCP00000058314

PDB

7W0Y, 7VY1