Reactome | NDUFA11 [mitochondrial inner membrane]

NDUFA11 [mitochondrial inner membrane]

Stable Identifier

R-SSC-163923

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

mitochondrial inner membrane

Synonyms

NDUFA11, I3LGM4

Locations in the PathwayBrowser

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Metabolism (Sus scrofa)

- Aerobic respiration and respiratory electron transport (Sus scrofa)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Sus scrofa)
    - Respiratory electron transport (Sus scrofa)
      - Complex I biogenesis (Sus scrofa)
        
        Intermediate 1 binds HP subcomplex to form Intermediate 2 (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Sus scrofa)
        
        980kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Sus scrofa)
        
        Complex I [mitochondrial inner membrane] (Sus scrofa)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Sus scrofa)
        
        HP subcomplex [mitochondrial inner membrane] (Sus scrofa)
        
        NDUFA11 [mitochondrial inner membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LGM4

Gene Names

NDUFA11

Reference Genes

BioGPS Gene:100514033 NDUFA11

ENSEMBL:ENSSSCG00000027307.3

ENSEMBL:ENSSSCG00005032924.1 NDUFA11

KEGG Gene (Sus scrofa):100514033 NDUFA11

Monarch:100514033 NDUFA11

NCBI Gene:100514033 NDUFA11

Reference Transcript

RefSeq:NM_001244924.1 NDUFA11

Other Identifiers

100514033

GO:0005739

GO:0005743

GO:0005747

GO:0007005

GO:0016020

GO:0032981

GO:0043226

GO:0065003

Ssc.24943.1.S1_at

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Sus scrofa)

Inferred From

NDUFA11 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_001231853.1

OpenTargets

ENSG00000174886

Ensembl

ENSSSCP00000023218, ENSSSCG00000027307, ENSSSCT00000024184

VGNC

100310

PDB

7V33, 7W1Z, 7VZ8, 7W0R, 7W2K, 7W2R, 7VXS, 7V2C, 7V2D, 7W4C, 7W31, 7VY9, 7W4E, 7V2F, 7VZW, 7W4G, 7W4K, 7VBP, 7W4M, 7W35, 7W1O, 7V2K, 7W1T, 7VWL, 7W20, 7V30, 7VYG, 7W1V, 7W4Q, 7V32, 7VYS, 7W0H, 7W2L, 7W0Y, 5GUP, 7V3M, 7VY1, 7W4D, 7W2U, 7VZV, 7W2Y, 7W4F, 7W32, 7V2E, 7VBL, 7W00, 7VC0, 7W4J, 7V2H, 7W1P, 7VYE, 7W4L, 5GPN, 7W4N, 7W1U, 7VYI, 7V2R, 7V31

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