Reactome | GJA1 [plasma membrane]

GJA1 [plasma membrane]

Stable Identifier

R-SSC-158058

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

GJA1, F1SF43

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Gap junction trafficking and regulation (Sus scrofa)
    - Gap junction trafficking (Sus scrofa)
      - Gap junction degradation (Sus scrofa)
        
        Formation of annular gap junctions (Sus scrofa)
        
        Dab2 is recruited to the junctional plaques (Sus scrofa)
        
        planar gap junction plaques [plasma membrane] (Sus scrofa)
        
        gap junction plaque [plasma membrane] (Sus scrofa)
        
        Junctional channel [plasma membrane] (Sus scrofa)
        
        Hemi-channels [plasma membrane] (Sus scrofa)
        
        Connexin 43 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques associated with Dab2 [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques [plasma membrane] (Sus scrofa)
        
        gap junction plaque [plasma membrane] (Sus scrofa)
        
        Junctional channel [plasma membrane] (Sus scrofa)
        
        Hemi-channels [plasma membrane] (Sus scrofa)
        
        Connexin 43 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)
        
        Dynamin is recruited to the gap junction plaque (Sus scrofa)
        
        Planar gap junction plaques associated with Dab2 and Dynamin [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques associated with Dab2 [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques [plasma membrane] (Sus scrofa)
        
        gap junction plaque [plasma membrane] (Sus scrofa)
        
        Junctional channel [plasma membrane] (Sus scrofa)
        
        Hemi-channels [plasma membrane] (Sus scrofa)
        
        Connexin 43 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques associated with Dab2 [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques [plasma membrane] (Sus scrofa)
        
        gap junction plaque [plasma membrane] (Sus scrofa)
        
        Junctional channel [plasma membrane] (Sus scrofa)
        
        Hemi-channels [plasma membrane] (Sus scrofa)
        
        Connexin 43 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)
        
        Internalization of gap junction plaques (Sus scrofa)
        
        Planar gap junction plaques associated with Dab2 and Dynamin [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques associated with Dab2 [plasma membrane] (Sus scrofa)
        
        planar gap junction plaques [plasma membrane] (Sus scrofa)
        
        gap junction plaque [plasma membrane] (Sus scrofa)
        
        Junctional channel [plasma membrane] (Sus scrofa)
        
        Hemi-channels [plasma membrane] (Sus scrofa)
        
        Connexin 43 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)
    - Regulation of gap junction activity (Sus scrofa)
      - Phosphorylation of Cx43 by c-src (Sus scrofa)
        
        Cx43:ZO-1:c-src gap junction [plasma membrane] (Sus scrofa)
        
        Cx43:ZO-1:c-src hemi-channel [plasma membrane] (Sus scrofa)
        
        6xGJA1:6xTJP1 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)
      - c-src associates with Cx43 in gap junctions (Sus scrofa)
        
        Cx43 :ZO-1 gap junction [plasma membrane] (Sus scrofa)
        
        6xGJA1:6xTJP1 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)
        
        Cx43:ZO-1:c-src gap junction [plasma membrane] (Sus scrofa)
        
        Cx43:ZO-1:c-src hemi-channel [plasma membrane] (Sus scrofa)
        
        6xGJA1:6xTJP1 hemi-channel [plasma membrane] (Sus scrofa)
        
        GJA1 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SF43

Gene Names

GJA1

Reference Genes

BioGPS Gene:100518636 GJA1

ENSEMBL:ENSSSCG00000004241.5

KEGG:ssc:100518636 GJA1

Monarch:100518636 GJA1

NCBI Gene:100518636 GJA1

UCSC:F1SF43 GJA1

Reference Transcript

RefSeq:NM_001244212.1 GJA1

Other Identifiers

100518636

GO:0000132

GO:0005243

GO:0005654

GO:0005737

GO:0005739

GO:0005886

GO:0005921

GO:0005922

GO:0007010

GO:0007154

GO:0007165

GO:0007267

GO:0007507

GO:0008013

GO:0008092

GO:0008104

GO:0010628

GO:0010644

GO:0014704

GO:0015075

GO:0015631

GO:0016020

GO:0022857

GO:0030054

GO:0032277

GO:0034220

GO:0044291

GO:0048856

GO:0055077

GO:0055085

GO:0070160

GO:0070161

GO:1901164

GO:1903763

GO:1904707

GO:1905332

GO:1905772

GO:2000648

Ssc.15912.1.S1_at

Ssc.29187.1.A1_at

Ssc.942.1.S1_at

Participates

as a candidate of

as a component of

Other forms of this molecule

GJA1 [Golgi membrane]

GJA1 [endoplasmic reticulum membrane]

GJA1 [lysosomal membrane]

phospho-GJA1 [plasma membrane]

GJA1 [Golgi-associated vesicle membrane]

Inferred From

GJA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001231141.1

ENSEMBL

ENSSSCT00000062855, ENSSSCT00000004688, ENSSSCP00000041147, ENSSSCP00000004580, ENSSSCG00000004241

VGNC

103098

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