Reactome | SOCS6 [cytosol]

SOCS6 [cytosol]

Stable Identifier

R-SSC-1469969

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

SOCS6, C9DRN1

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Neddylation (Sus scrofa)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        SOCS6 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        SOCS6 [cytosol] (Sus scrofa)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Sus scrofa)
        
        CRL E3 ubiquitin ligases [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        SOCS6 [cytosol] (Sus scrofa)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        SOCS6 [cytosol] (Sus scrofa)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Sus scrofa)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        SOCS6 [cytosol] (Sus scrofa)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Sus scrofa)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Sus scrofa)
        
        CUL5-box protein [cytosol] (Sus scrofa)
        
        SOCS6 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:C9DRN1

Gene Names

SOCS6

Reference Genes

BioGPS Gene:100155619 SOCS6

ENSEMBL:ENSSSCG00000032214.3

KEGG:ssc:100155619 SOCS6

Monarch:100155619 SOCS6

NCBI Gene:100155619 SOCS6

UCSC:C9DRN1 SOCS6

Reference Transcript

Other Identifiers

100155619

GO:0001772

GO:0005829

GO:0009968

GO:0010498

GO:0016567

GO:0030163

GO:0035556

GO:0035591

GO:0040008

GO:0050868

GO:0060090

Ssc.21358.1.S1_at

Ssc.22685.1.S1_at

Ssc.29076.1.A1_at

Ssc.29718.1.A1_at

Participates

as an input of

Active FLT3 binds to SOCS6 (Sus scrofa)

as a component of

active FLT3:SOCS6 [plasma membrane] (Sus scrofa)

as a candidate of

FLT3 ubiquitin ligases [cytosol] (Sus scrofa)

as a member of

CUL5-box protein [cytosol] (Sus scrofa)

Inferred From

SOCS6 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001163989.1, XP_020949449.1

ENSEMBL

ENSSSCG00000032214, ENSSSCT00000059603, ENSSSCP00000066829, ENSSSCT00000073983, ENSSSCT00000054675, ENSSSCP00000043456, ENSSSCP00000059106

VGNC

93333