Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-LRP6 [plasma membrane]
Stable Identifier
R-SSC-1458895
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
plasma membrane
Synonyms
p-4S,3T,T1479,S1490,T1493-LRP6, A0A287AAJ4
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
Signaling by WNT (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Sus scrofa)
Beta-catenin is released from the destruction complex (Sus scrofa)
WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Sus scrofa)
p10S/T-LRP5/6 [plasma membrane] (Sus scrofa)
phospho-LRP6 [plasma membrane] (Sus scrofa)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Sus scrofa)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Sus scrofa)
phospho-LRP6 [plasma membrane] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287AAJ4
Gene Names
LRP6
Reference Genes
ENSEMBL:ENSSSCG00000000625.5
UCSC:A0A287AAJ4 LRP6
Other Identifiers
100515777
GO:0005041
GO:0005102
GO:0005109
GO:0005515
GO:0005768
GO:0005769
GO:0005783
GO:0005794
GO:0005886
GO:0005901
GO:0006355
GO:0006897
GO:0007399
GO:0009888
GO:0009986
GO:0014029
GO:0014033
GO:0015026
GO:0016020
GO:0016055
GO:0016192
GO:0017147
GO:0019210
GO:0019534
GO:0030154
GO:0030291
GO:0030901
GO:0031410
GO:0034392
GO:0038024
GO:0042802
GO:0042803
GO:0042813
GO:0042981
GO:0043009
GO:0045121
GO:0045787
GO:0045893
GO:0045944
GO:0048646
GO:0048856
GO:0055085
GO:0060070
GO:0071397
GO:0071542
GO:0072659
GO:0098772
GO:1990851
GO:1990909
Ssc.4693.1.S1_at
Ssc.4693.2.S1_at
Ssc.4693.3.S1_a_at
Ssc.4693.3.S1_at
Participates
as a component of
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Sus scrofa)
as a member of
p10S/T-LRP5/6 [plasma membrane] (Sus scrofa)
Other forms of this molecule
LRP6 [early endosome membrane]
phospho-LRP6 [early endosome membrane]
phospho-LRP6 [plasma membrane]
LRP6 [plasma membrane]
Inferred From
p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1490 (in Homo sapiens)
Coordinate
1490
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 1479 (in Homo sapiens)
Coordinate
1479
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 1493 (in Homo sapiens)
Coordinate
1493
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ENSEMBL
ENSSSCT00000039050
,
ENSSSCG00000000625
,
ENSSSCP00000040912
VGNC
89821
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text