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phospho-SHC1 [plasma membrane]
Stable Identifier
R-SSC-1169439
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
plasma membrane
Synonyms
p-Y194,Y195,Y272-SHC1-3, A0A5K1V5Y3
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
RAS GEFs [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR2:pY-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR2:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR3:pY-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR3:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR4:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by ALK (Sus scrofa)
Active ALK phosphorylates SHC1 (Sus scrofa)
Active ALK:p-3Y SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Signaling by FGFR (Sus scrofa)
Signaling by FGFR1 (Sus scrofa)
Downstream signaling of activated FGFR1 (Sus scrofa)
SHC-mediated cascade:FGFR1 (Sus scrofa)
Activated FGFR1 phosphorylates SHC1 (Sus scrofa)
Activated FGFR1:p-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Sus scrofa)
Activated FGFR1:p-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Signaling by FGFR2 (Sus scrofa)
Downstream signaling of activated FGFR2 (Sus scrofa)
SHC-mediated cascade:FGFR2 (Sus scrofa)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR2:pY-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR2:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Signaling by FGFR3 (Sus scrofa)
Downstream signaling of activated FGFR3 (Sus scrofa)
SHC-mediated cascade:FGFR3 (Sus scrofa)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR3:pY-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR3:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Signaling by FGFR4 (Sus scrofa)
Downstream signaling of activated FGFR4 (Sus scrofa)
SHC-mediated cascade:FGFR4 (Sus scrofa)
Activated FGFR4 phosphorylates SHC1 (Sus scrofa)
Activated FGFR4:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Sus scrofa)
Activated FGFR4:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR4:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Sus scrofa)
Activated FGFR4:pY-SHC1 [plasma membrane] (Sus scrofa)
phospho-SHC1 [plasma membrane] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5K1V5Y3
Gene Names
SHC1
Reference Genes
BioGPS Gene:100156321 SHC1
ENSEMBL:ENSSSCG00000006539.6
KEGG Gene (Sus scrofa):100156321 SHC1
Monarch:100156321 SHC1
NCBI Gene:100156321 SHC1
Reference Transcript
RefSeq:XM_001929397.4 SHC1
Other Identifiers
100156321
GO:0001525
GO:0001784
GO:0005068
GO:0005158
GO:0005159
GO:0005168
GO:0005737
GO:0005886
GO:0006351
GO:0006355
GO:0007010
GO:0007155
GO:0007173
GO:0007507
GO:0008286
GO:0012501
GO:0023052
GO:0030036
GO:0030971
GO:0035556
GO:0042127
GO:0042742
GO:0043066
GO:0043410
GO:0045892
GO:0045893
GO:0046875
GO:0048009
GO:0048408
GO:0048856
GO:0060090
GO:0070374
GO:0071363
GO:0098542
GO:0098609
Ssc.5093.1.A1_at
Ssc.5093.2.S1_at
Participates
as a component of
Active ALK:p-3Y SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR3:pY-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR1:p-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR4:pY-SHC1 [plasma membrane] (Sus scrofa)
Activated FGFR2:pY-SHC1 [plasma membrane] (Sus scrofa)
Other forms of this molecule
SHC1 [plasma membrane]
SHC1 [plasma membrane]
SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
SHC1 [cytosol]
SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [cytosol]
phospho-SHC1 [plasma membrane]
phospho-SHC1 [cytosol]
SHC1 [cytosol]
phospho-SHC1 [cytosol]
Inferred From
p-SHC1 p46,p52 [plasma membrane]
(Homo sapiens)
p-Y194,Y195,Y272-SHC1-3 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 194 (in Homo sapiens)
Coordinate
194
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 195 (in Homo sapiens)
Coordinate
195
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 272 (in Homo sapiens)
Coordinate
272
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_001929432.1
OpenTargets
ENSG00000160691
Ensembl
ENSSSCP00000028571
,
ENSSSCG00000006539
,
ENSSSCT00000034547
VGNC
92837
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