Reactome | rps1401 [cytosol]

rps1401 [cytosol]

Stable Identifier

R-SPO-72333

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

RPS14, P0CT56

Locations in the PathwayBrowser

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Metabolism of RNA (Schizosaccharomyces pombe)

- Nonsense-Mediated Decay (NMD) (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS14 [cytosol] (Schizosaccharomyces pombe)
        
        rps1401 [cytosol] (Schizosaccharomyces pombe)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS14 [cytosol] (Schizosaccharomyces pombe)
        
        rps1401 [cytosol] (Schizosaccharomyces pombe)
    - SMG6 hydrolyzes mRNA with premature termination codon (Schizosaccharomyces pombe)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS14 [cytosol] (Schizosaccharomyces pombe)
        
        rps1401 [cytosol] (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Schizosaccharomyces pombe)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS14 [cytosol] (Schizosaccharomyces pombe)
        
        rps1401 [cytosol] (Schizosaccharomyces pombe)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS14 [cytosol] (Schizosaccharomyces pombe)
        
        rps1401 [cytosol] (Schizosaccharomyces pombe)
- rRNA processing (Schizosaccharomyces pombe)
  - rRNA processing in the nucleus and cytosol (Schizosaccharomyces pombe)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Schizosaccharomyces pombe)
      - 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Schizosaccharomyces pombe)
        
        40S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        Homologues of RPS14 [cytosol] (Schizosaccharomyces pombe)
        
        rps1401 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P0CT56

Gene Names

rps1401

Reference Genes

BioGPS Gene:2540817 rps1401

ENSEMBL:SPAC3H5.05c

KEGG:spo:2540817 rps1402

KEGG:spo:5802781 rps1402

Monarch:2540817 rps1401

NCBI Gene:2540817 rps1401

PomBase:SPAC3H5.05c

UCSC:P0CT56 rps1401

Reference Transcript

RefSeq:NM_001019611.2 rps1401

Participates

as a member of

Homologues of RPS14 [cytosol] (Schizosaccharomyces pombe)

Other forms of this molecule

rps1401 [nucleoplasm]

Inferred From

RPS14 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_594187.1

PRO

P0CT56

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