Reactome | rad3 [nucleoplasm]

rad3 [nucleoplasm]

Stable Identifier

R-SPO-69484-2

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

ATM, Q02099

Locations in the PathwayBrowser

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Cellular responses to stimuli (Schizosaccharomyces pombe)

- Cellular responses to stress (Schizosaccharomyces pombe)
  - Cellular Senescence (Schizosaccharomyces pombe)
    - DNA Damage/Telomere Stress Induced Senescence (Schizosaccharomyces pombe)
      - KAT5 acetylates ATM at DNA DSBs (Schizosaccharomyces pombe)
        
        DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Schizosaccharomyces pombe)
        
        dimeric ATM kinase [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of ATM [nucleoplasm] (Schizosaccharomyces pombe)
        
        rad3 [nucleoplasm] (Schizosaccharomyces pombe)
      - KAT5 acetylates ATM at shortened telomeres (Schizosaccharomyces pombe)
        
        Shortened telomere:MRN:ATM dimer:KAT5 [nucleoplasm] (Schizosaccharomyces pombe)
        
        ATM dimer:KAT5 [nucleoplasm] (Schizosaccharomyces pombe)
        
        dimeric ATM kinase [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of ATM [nucleoplasm] (Schizosaccharomyces pombe)
        
        rad3 [nucleoplasm] (Schizosaccharomyces pombe)

DNA Repair (Schizosaccharomyces pombe)

- DNA Double-Strand Break Repair (Schizosaccharomyces pombe)
  - DNA Double Strand Break Response (Schizosaccharomyces pombe)
    - Sensing of DNA Double Strand Breaks (Schizosaccharomyces pombe)
      - KAT5 acetylates ATM at DNA DSBs (Schizosaccharomyces pombe)
        
        DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Schizosaccharomyces pombe)
        
        dimeric ATM kinase [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of ATM [nucleoplasm] (Schizosaccharomyces pombe)
        
        rad3 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:Q02099

Gene Names

rad3

Reference Genes

BioGPS Gene:2540719 rad3

ENSEMBL:SPBC216.05

KEGG:spo:2540719 rad3

Monarch:2540719 rad3

NCBI Gene:2540719 rad3

PomBase:SPBC216.05

UCSC:Q02099 rad3

Reference Transcript

RefSeq:NM_001021264.2 rad3

Participates

as a member of

Homologues of ATM [nucleoplasm] (Schizosaccharomyces pombe)

Other forms of this molecule

rad3 [nucleoplasm]

phospho-rad3 [nucleoplasm]

rad3 [peroxisomal matrix]

rad3 [cytosol]

Inferred From

ATM [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_595357.1

PRO

Q02099

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