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CDK2 [nucleoplasm]
Stable Identifier
R-SPO-68365
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Synonyms
P04551
Locations in the PathwayBrowser
Expand all
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle Checkpoints (Schizosaccharomyces pombe)
G2/M Checkpoints (Schizosaccharomyces pombe)
Activation of ATR in response to replication stress (Schizosaccharomyces pombe)
Loading of claspin onto DNA during replication origin firing (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
Mitotic G1 phase and G1/S transition (Schizosaccharomyces pombe)
G1/S Transition (Schizosaccharomyces pombe)
Activation of the pre-replicative complex (Schizosaccharomyces pombe)
CDK and DDK associate with the Mcm10:pre-replicative complex (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Cdc45 associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase alpha:primase binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase epsilon binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Cyclin E associated events during G1/S transition (Schizosaccharomyces pombe)
CAK-mediated phosphorylation of Cyclin E:Cdk2 (Schizosaccharomyces pombe)
CCNE:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Schizosaccharomyces pombe)
CCNE:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Translocation of Cyclin E:Cdk2 complex to the nucleus (Schizosaccharomyces pombe)
CCNE:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
S Phase (Schizosaccharomyces pombe)
Cyclin A:Cdk2-associated events at S phase entry (Schizosaccharomyces pombe)
CAK-mediated phosphorylation of Cyclin A:Cdk2 (Schizosaccharomyces pombe)
CCNA:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Schizosaccharomyces pombe)
CCNA:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Translocation of Cyclin A:Cdk2 complexes to the nucleus (Schizosaccharomyces pombe)
CCNA:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication (Schizosaccharomyces pombe)
DNA Replication Pre-Initiation (Schizosaccharomyces pombe)
Activation of the pre-replicative complex (Schizosaccharomyces pombe)
CDK and DDK associate with the Mcm10:pre-replicative complex (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
Cdc45 associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase alpha:primase binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase epsilon binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:P04551
Reference Genes
ENSEMBL:SPBC11B10.09
PomBase:SPBC11B10.09
UCSC:P04551
Participates
as a component of
CCNE:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CCNA:CDK2 [nucleoplasm] (Schizosaccharomyces pombe)
CDK [nucleoplasm] (Schizosaccharomyces pombe)
Other forms of this molecule
phospho-p-Y15-CDK2 [nucleoplasm]
phospho-p-CDK2 [nucleoplasm]
CDK2 [cytosol]
CDK4 [cytosol]
CDK6 [cytosol]
CDK4 [nucleoplasm]
CDK6 [nucleoplasm]
phospho-p-T172-CDK4 [nucleoplasm]
phospho-p-T177-CDK6 [nucleoplasm]
phospho-p-T160-CDK2 [nucleoplasm]
Inferred From
CDK2 [nucleoplasm]
(Homo sapiens)
Cross References
PRO
P04551
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O74627
3
pch1 [nucleoplasm]
(R-SPO-51613)
pch1 [nucleoplasm]
(R-SPO-6796619-2)
pch1 [nucleoplasm]
(R-SPO-51611-2)
0.508
2
UniProt:Q09142
1
orc2 [nucleoplasm]
(R-SPO-68405)
0.508
2
UniProt:P40380 RUM1
0.499
2
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