Reactome | phospho-atf21 [nucleoplasm]

phospho-atf21 [nucleoplasm]

Stable Identifier

R-SPO-450243-2

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

p-T69,T71-ATF2, P78962

Locations in the PathwayBrowser

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Immune System (Schizosaccharomyces pombe)

- Cytokine Signaling in Immune system (Schizosaccharomyces pombe)
  - Signaling by Interleukins (Schizosaccharomyces pombe)
    - Interleukin-17 signaling (Schizosaccharomyces pombe)
      - MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
- Innate Immune System (Schizosaccharomyces pombe)
  - Toll-like Receptor Cascades (Schizosaccharomyces pombe)
    - Toll Like Receptor 10 (TLR10) Cascade (Schizosaccharomyces pombe)
      - MyD88 cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 2 (TLR2) Cascade (Schizosaccharomyces pombe)
      - Toll Like Receptor TLR1:TLR2 Cascade (Schizosaccharomyces pombe)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
      - Toll Like Receptor TLR6:TLR2 Cascade (Schizosaccharomyces pombe)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 3 (TLR3) Cascade (Schizosaccharomyces pombe)
      - MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 4 (TLR4) Cascade (Schizosaccharomyces pombe)
      - MyD88-independent TLR4 cascade (Schizosaccharomyces pombe)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 5 (TLR5) Cascade (Schizosaccharomyces pombe)
      - MyD88 cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Schizosaccharomyces pombe)
      - MyD88 dependent cascade initiated on endosome (Schizosaccharomyces pombe)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 9 (TLR9) Cascade (Schizosaccharomyces pombe)
      - MyD88 dependent cascade initiated on endosome (Schizosaccharomyces pombe)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        Activation of the AP-1 family of transcription factors (Schizosaccharomyces pombe)
        
        Phosphorylated MAPKs phosphorylate ATF-2 (Schizosaccharomyces pombe)
        
        Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-atf21 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P78962

Gene Names

atf21

Reference Genes

BioGPS Gene:2540363 atf21

ENSEMBL:SPBC2F12.09c

KEGG:spo:2540363 atf21

Monarch:2540363 atf21

NCBI Gene:2540363 atf21

PomBase:SPBC2F12.09c

UCSC:P78962 atf21

Reference Transcript

RefSeq:NM_001021604.2 atf21

Participates

as a member of

Homologues of p-T69,T71-ATF2 [nucleoplasm] (Schizosaccharomyces pombe)

Other forms of this molecule

atf21 [nucleoplasm]

Inferred From

p-T69,T71-ATF2 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 71 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-threonine at 69 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_595707.1

PRO

P78962

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