Reactome | pmp1 [nucleoplasm]

pmp1 [nucleoplasm]

Stable Identifier

R-SPO-203791

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

DUSP7, O13453

Locations in the PathwayBrowser

Expand all

Immune System (Schizosaccharomyces pombe)

- Cytokine Signaling in Immune system (Schizosaccharomyces pombe)
  - Signaling by Interleukins (Schizosaccharomyces pombe)
    - Interleukin-17 signaling (Schizosaccharomyces pombe)
      - MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
- Innate Immune System (Schizosaccharomyces pombe)
  - Toll-like Receptor Cascades (Schizosaccharomyces pombe)
    - Toll Like Receptor 10 (TLR10) Cascade (Schizosaccharomyces pombe)
      - MyD88 cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 2 (TLR2) Cascade (Schizosaccharomyces pombe)
      - Toll Like Receptor TLR1:TLR2 Cascade (Schizosaccharomyces pombe)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
      - Toll Like Receptor TLR6:TLR2 Cascade (Schizosaccharomyces pombe)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 3 (TLR3) Cascade (Schizosaccharomyces pombe)
      - MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 4 (TLR4) Cascade (Schizosaccharomyces pombe)
      - MyD88-independent TLR4 cascade (Schizosaccharomyces pombe)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 5 (TLR5) Cascade (Schizosaccharomyces pombe)
      - MyD88 cascade initiated on plasma membrane (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Schizosaccharomyces pombe)
      - MyD88 dependent cascade initiated on endosome (Schizosaccharomyces pombe)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)
    - Toll Like Receptor 9 (TLR9) Cascade (Schizosaccharomyces pombe)
      - MyD88 dependent cascade initiated on endosome (Schizosaccharomyces pombe)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Schizosaccharomyces pombe)
        
        MAP kinase activation (Schizosaccharomyces pombe)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)

Signal Transduction (Schizosaccharomyces pombe)

- Signaling by Receptor Tyrosine Kinases (Schizosaccharomyces pombe)
  - Signaling by NTRKs (Schizosaccharomyces pombe)
    - Signaling by NTRK1 (TRKA) (Schizosaccharomyces pombe)
      - Nuclear Events (kinase and transcription factor activation) (Schizosaccharomyces pombe)
        
        ERK/MAPK targets (Schizosaccharomyces pombe)
        
        ERKs are inactivated (Schizosaccharomyces pombe)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Schizosaccharomyces pombe)
        
        pmp1 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:O13453

Gene Names

pmp1

Reference Genes

BioGPS Gene:2540019 pmp1

ENSEMBL:SPBC1685.01

KEGG:spo:2540019 pmp1

Monarch:2540019 pmp1

NCBI Gene:2540019 pmp1

PomBase:SPBC1685.01

UCSC:O13453 pmp1

Reference Transcript

RefSeq:NM_001021111.2 pmp1

Other forms of this molecule

pmp1 [nucleoplasm]

Inferred From

ERK-specific DUSP [nucleoplasm] (Homo sapiens)

DUSP7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_595205.1

IntEnz

3.1.3.48

PRO

O13453

Cite Us!