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MTHFD1 [cytosol]
Stable Identifier
R-SPO-200641
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
cytosol
Synonyms
O43007
Locations in the PathwayBrowser
Expand all
Metabolism (Schizosaccharomyces pombe)
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of folate and pterines (Schizosaccharomyces pombe)
5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Schizosaccharomyces pombe)
MTHFD1 dimer [cytosol] (Schizosaccharomyces pombe)
MTHFD1 [cytosol] (Schizosaccharomyces pombe)
5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Schizosaccharomyces pombe)
MTHFD1 dimer [cytosol] (Schizosaccharomyces pombe)
MTHFD1 [cytosol] (Schizosaccharomyces pombe)
MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Schizosaccharomyces pombe)
MTHFD1 dimer [cytosol] (Schizosaccharomyces pombe)
MTHFD1 [cytosol] (Schizosaccharomyces pombe)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Schizosaccharomyces pombe)
MTHFD1 dimer [cytosol] (Schizosaccharomyces pombe)
MTHFD1 [cytosol] (Schizosaccharomyces pombe)
MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Schizosaccharomyces pombe)
MTHFD1 dimer [cytosol] (Schizosaccharomyces pombe)
MTHFD1 [cytosol] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:O43007
Reference Genes
BioGPS Gene:2540300
ENSEMBL:SPBC2G2.08
KEGG:spo:2540300
Monarch:2540300
NCBI Gene:2540300
PomBase:SPBC2G2.08
UCSC:O43007
Reference Transcript
RefSeq:NM_001022356.2
Participates
as a component of
MTHFD1 dimer [cytosol] (Schizosaccharomyces pombe)
Other forms of this molecule
MTHFD2 [mitochondrial matrix]
MTHFD2L [mitochondrial matrix]
MTHFD1L [mitochondrial matrix]
Inferred From
MTHFD1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_596437.2
PRO
O43007
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