Reactome | cut9 [cytosol]

cut9 [cytosol]

Stable Identifier

R-SPO-174156

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

CDC16, P41889

Locations in the PathwayBrowser

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Cell Cycle (Schizosaccharomyces pombe)

- Cell Cycle, Mitotic (Schizosaccharomyces pombe)
  - Regulation of mitotic cell cycle (Schizosaccharomyces pombe)
    - APC/C-mediated degradation of cell cycle proteins (Schizosaccharomyces pombe)
      - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Schizosaccharomyces pombe)
        
        APC/C:Cdc20 mediated degradation of mitotic proteins (Schizosaccharomyces pombe)
        
        APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Schizosaccharomyces pombe)
        
        APC-Cdc20 mediated degradation of Nek2A (Schizosaccharomyces pombe)
        
        Association of Nek2A with MCC:APC/C (Schizosaccharomyces pombe)
        
        MCC:APC/C complex [cytosol] (Schizosaccharomyces pombe)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Schizosaccharomyces pombe)
        
        cut9 [cytosol] (Schizosaccharomyces pombe)
        
        Nek2A:MCC:APC/C complex [cytosol] (Schizosaccharomyces pombe)
        
        MCC:APC/C complex [cytosol] (Schizosaccharomyces pombe)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Schizosaccharomyces pombe)
        
        cut9 [cytosol] (Schizosaccharomyces pombe)

Immune System (Schizosaccharomyces pombe)

- Adaptive Immune System (Schizosaccharomyces pombe)
  - Class I MHC mediated antigen processing & presentation (Schizosaccharomyces pombe)
    - Antigen processing: Ubiquitination & Proteasome degradation (Schizosaccharomyces pombe)
      - Release of E3 from polyubiquitinated substrate (Schizosaccharomyces pombe)
        
        E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
        
        APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
        
        cut9 [cytosol] (Schizosaccharomyces pombe)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Schizosaccharomyces pombe)
        
        E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
        
        APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
        
        cut9 [cytosol] (Schizosaccharomyces pombe)
      - Transfer of Ub from E2 to substrate and release of E2 (Schizosaccharomyces pombe)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Schizosaccharomyces pombe)
        
        E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
        
        APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
        
        cut9 [cytosol] (Schizosaccharomyces pombe)
        
        E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
        
        APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
        
        cut9 [cytosol] (Schizosaccharomyces pombe)
        
        E3:Ub:substrate [cytosol] (Schizosaccharomyces pombe)
        
        E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
        
        APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
        
        cut9 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P41889

Gene Names

cut9

Reference Genes

BioGPS Gene:2541592 cut9

ENSEMBL:SPAC6F12.15c

KEGG:spo:2541592 cut9

Monarch:2541592 cut9

NCBI Gene:2541592 cut9

PomBase:SPAC6F12.15c

UCSC:P41889 cut9

Reference Transcript

RefSeq:NM_001018731.2 cut9

Participates

as a component of

Other forms of this molecule

cut9 [nucleoplasm]

Inferred From

CDC16 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_593301.1

PRO

P41889

PDB

2XPI