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slp1 [cytosol]
Stable Identifier
R-SPO-141412
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
cytosol
Synonyms
CDC20, P78972
Locations in the PathwayBrowser
Expand all
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle Checkpoints (Schizosaccharomyces pombe)
Mitotic Spindle Checkpoint (Schizosaccharomyces pombe)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Schizosaccharomyces pombe)
Inactivation of APC/C via CDC20 sequestration (Schizosaccharomyces pombe)
MAD2*CDC20 complex [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
Inactivation of APC/C via direct inhibition of the APC/C complex (Schizosaccharomyces pombe)
Formation of the MCC complex (Schizosaccharomyces pombe)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
Regulation of mitotic cell cycle (Schizosaccharomyces pombe)
APC/C-mediated degradation of cell cycle proteins (Schizosaccharomyces pombe)
Regulation of APC/C activators between G1/S and early anaphase (Schizosaccharomyces pombe)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Schizosaccharomyces pombe)
Inactivation of APC/C via CDC20 sequestration (Schizosaccharomyces pombe)
MAD2*CDC20 complex [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
Inactivation of APC/C via direct inhibition of the APC/C complex (Schizosaccharomyces pombe)
Formation of the MCC complex (Schizosaccharomyces pombe)
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
Immune System (Schizosaccharomyces pombe)
Adaptive Immune System (Schizosaccharomyces pombe)
Class I MHC mediated antigen processing & presentation (Schizosaccharomyces pombe)
Antigen processing: Ubiquitination & Proteasome degradation (Schizosaccharomyces pombe)
Release of E3 from polyubiquitinated substrate (Schizosaccharomyces pombe)
E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
Cdc20/Cdh1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
E3:K48-polyubiquitinated substrate [cytosol] (Schizosaccharomyces pombe)
E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
Cdc20/Cdh1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
Transfer of Ub from E2 to substrate and release of E2 (Schizosaccharomyces pombe)
Ag-substrate:E3:E2:Ub [cytosol] (Schizosaccharomyces pombe)
E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
Cdc20/Cdh1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
Cdc20/Cdh1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
E3:Ub:substrate [cytosol] (Schizosaccharomyces pombe)
E3 ligases in proteasomal degradation [cytosol] (Schizosaccharomyces pombe)
APC/C E3 ligase complex [cytosol] (Schizosaccharomyces pombe)
Cdc20/Cdh1 [cytosol] (Schizosaccharomyces pombe)
slp1 [cytosol] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:P78972
Gene Names
slp1
Reference Genes
BioGPS Gene:2543222 slp1
ENSEMBL:SPAC821.08c
GeneDB:SPAC821.08c
KEGG Gene (Sc):SPAC821.08c slp1
Monarch:2543222 slp1
NCBI Gene:2543222 slp1
Reference Transcript
RefSeq:NM_001018559.2 slp1
Participant Of
hasMember
Cdc20/Cdh1 [cytosol]
input
Formation of the MCC complex
Inactivation of APC/C via CDC20 sequestration
hasComponent
hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol]
MAD2*CDC20 complex [cytosol]
Other forms of this molecule
slp1 [nucleoplasm]
Inferred From
CDC20 [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_593161.1
PRO
P78972
PDB
4AEZ
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14417
1
mad2 [cytosol]
(R-SPO-141447)
0.756
8
UniProt:O59767 MAD3
0.527
2
UniProt:P41005 MES1
0.524
2
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