Reactome | RQC1 [cytosol]

RQC1 [cytosol]

Stable Identifier

R-SCE-9950013

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

fullName evidence="7"Ribosome quality control complex subunit 1, RQC1_YEAST

External Reference Information

External Reference

UniProt:Q05468 RQC1

Gene Names

RQC1, YDR333C

Chain

chain:1-723

Reference Genes

BioGPS Gene:851933 RQC1

KEGG:sce:YDR333C RQC1

Monarch:851933 RQC1

NCBI Gene:851933 RQC1

UCSC:Q05468 RQC1

Reference Transcript

RefSeq:NM_001180641.3 RQC1

Other Identifiers

851933

GO:0003674

GO:0005575

GO:0005737

GO:0006414

GO:0030674

GO:0051603

GO:0060090

GO:0072344

GO:1990112

GO:1990116

Participates

as an output of

The proteasome degrades the K48-polyUb nascent peptide-Ala-Thr bound to RKR1:RQC2:RQC1:CDC48 hexamer (Saccharomyces cerevisiae)

as a component of

Other forms of this molecule

RQC1 [cytosol]

Cross References

RefSeq

NP_010620.3

ENSEMBL

YDR333C_mRNA, YDR333C, YDR333C

PRO

Q05468

PDB

9OFV

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P14126 RPL3	3	RPL3 [cytosol] (R-SCE-72450) RPL3 [cytosol] (R-SCE-72448) RPL3 [cytosol] (R-SCE-9633189)	0.527	2
UniProt:P26321 RPL5	1	RPL5 [cytosol] (R-SCE-9633136)	0.527	2
UniProt:P02406 RPL28	4	RPL28 [cytosol] (R-SCE-72442) RPL28 [cytosol] (R-SCE-9633254) RPL28 [nucleoplasm] (R-SCE-9630984) RPL28 [nucleoplasm] (R-SCE-9630970)	0.527	2
UniProt:P04456 RPL25	2	RPL25 [cytosol] (R-SCE-72432) RPL25 [cytosol] (R-SCE-9633157)	0.527	2
UniProt:P38061 RPL32	2	RPL32 [cytosol] (R-SCE-9633137) RPL32 [cytosol] (R-SCE-72456)	0.527	2
UniProt:P05317	1	RPP0 [cytosol] (R-SCE-72396)	0.527	2
UniProt:Q12532 RQC2	2	RQC2 [cytosol] (R-SCE-9950031) RQC2 [cytosol] (R-SCE-9948358)	0.527	3

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