Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TEP1 [cytosol]
Stable Identifier
R-SCE-8948777
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
K48polyUb-K289-PTEN, P53916
Locations in the PathwayBrowser
Expand all
Signal Transduction (Saccharomyces cerevisiae)
Intracellular signaling by second messengers (Saccharomyces cerevisiae)
PIP3 activates AKT signaling (Saccharomyces cerevisiae)
PTEN Regulation (Saccharomyces cerevisiae)
Regulation of PTEN stability and activity (Saccharomyces cerevisiae)
Proteasome degrades polyubiquitinated PTEN (Saccharomyces cerevisiae)
PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (Saccharomyces cerevisiae)
TEP1 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P53916
Gene Names
TEP1
Reference Genes
BioGPS Gene:855595 TEP1
ENSEMBL:YNL128W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YNL128W TEP1
Monarch:855595 TEP1
NCBI Gene:855595 TEP1
SGD:YNL128W
Reference Transcript
RefSeq:NM_001182966.4 TEP1
Other Identifiers
1773929_at
855595
8994_at
GO:0003674
GO:0004725
GO:0005575
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006629
GO:0008138
GO:0008150
GO:0016020
GO:0016311
GO:0016314
GO:0016787
GO:0016791
GO:0023052
GO:0030476
GO:0042995
GO:0043491
GO:0043934
GO:0046856
GO:0048870
GO:0051321
GO:0051896
GO:0071554
Participates
as a member of
PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
TEP1 [cytosol]
TEP1 [nucleoplasm]
phospho-TEP1 [cytosol]
phospho-TEP1 [cytosol]
phospho-TEP1 [cytosol]
TEP1 [cytosol]
TEP1 [cytosol]
TEP1 [nucleoplasm]
TEP1 [nucleoplasm]
TEP1 [Golgi membrane]
TEP1 [Golgi membrane]
TEP1 [cytosol]
Inferred From
PolyUb-PTEN,K48polyUb-K289-PTEN [cytosol]
(Homo sapiens)
K48polyUb-K289-PTEN [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 289 (in Homo sapiens)
Coordinate
289
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_014271.3
OpenTargets
ENSG00000129566
IntEnz
3.1.3.67
PRO
P53916
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text