Reactome | RPL11A [cytosol]

RPL11A [cytosol]

Stable Identifier

R-SCE-72406

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

RPL11, P0C0W9

Locations in the PathwayBrowser

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Metabolism of RNA (Saccharomyces cerevisiae)

- Nonsense-Mediated Decay (NMD) (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Saccharomyces cerevisiae)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL11A [cytosol] (Saccharomyces cerevisiae)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL11A [cytosol] (Saccharomyces cerevisiae)
    - SMG6 hydrolyzes mRNA with premature termination codon (Saccharomyces cerevisiae)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL11A [cytosol] (Saccharomyces cerevisiae)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Saccharomyces cerevisiae)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL11A [cytosol] (Saccharomyces cerevisiae)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Saccharomyces cerevisiae)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Saccharomyces cerevisiae)
        
        80S ribosome [cytosol] (Saccharomyces cerevisiae)
        
        60S ribosomal complex [cytosol] (Saccharomyces cerevisiae)
        
        RPL11A [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P0C0W9 RPL11A

Gene Names

RPL11A, RP39A, RPL16A, YPR102C, P8283.14

Chain

initiator methionine:1, chain:2-174

Reference Genes

BioGPS Gene:856217 RPL11A

KEGG:sce:YPR102C RPL11A

Monarch:856217 RPL11A

NCBI Gene:856217 RPL11A

UCSC:P0C0W9 RPL11A

Reference Transcript

RefSeq:NM_001184199.1 RPL11A

Other Identifiers

856217

GO:0000027

GO:0002181

GO:0003723

GO:0003735

GO:0005198

GO:0005575

GO:0005634

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0019843

GO:0022625

GO:1990904

Participates

as a component of

Other forms of this molecule

RPL11A [cytosol]

Inferred From

RPL11 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_015427.1

ENSEMBL

YPR102C, YPR102C, YPR102C_mRNA

PRO

P0C0W9

PDB

7UOO, 6QT0, 6T7T, 8CIV, 6QTZ, 6N8N, 5M1J, 6N8M, 7ZUW, 4V8Y, 3J6Y, 8ZGY, 5JUP, 8CKU, 8AGV, 7UG6, 7ZRS, 8BQD, 8CCS, 9F9S, 5FCI, 6M62, 8CDR, 3JCT, 8CGN, 8K2D, 4V6I, 8P8M, 7ZW0, 6YLG, 6T83, 7MPI, 6N8J, 7N8B, 8T30, 4V7F, 7BT6, 5MC6, 5T62, 8T3B, 6Z6K, 5JUS, 4V5Z, 8T2Z, 4V7R, 5JUO, 3J77, 8HFR, 9OFV, 8T3C, 8T2Y, 6FT6, 8UT0, 8BQX, 7OHT, 5NDG, 8P8N, 8K82, 8P8U, 4V8Z, 8UTI, 6YLH, 4V4B, 5DGE, 6RZZ, 5FCJ, 4V88, 8PFR, 6N8O, 7MPJ, 6N8K, 5GAK, 8CMJ, 5JCS, 5APN, 5H4P, 7UQZ, 7BTB, 8AGX, 5JUU, 6SNT, 8T3E, 8T3D, 8BN3, 5T6R, 4V91, 8AAF, 3J78, 7OHQ, 6RI5, 6T7I, 7Z34, 7UQB, 7V08, 7OH3, 8CEH, 8AGZ, 8AGU, 6N8L, 8P9A, 8CF5, 8T2X, 6Z6J, 3J6X, 5APO, 9F58, 8AGT, 8AGW, 6S05, 8CG8, 5JUT, 6HD7, 6QIK, 8T3F, 8CDL, 8T3A, 6SV4

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38333	2	ENP1 [nucleoplasm] (R-SCE-6791526) ENP1 [cytosol] (R-SCE-6791518)	0.527	2

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