Reactome | SLY1 [cytosol]

SLY1 [cytosol]

Stable Identifier

R-SCE-5688147

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

SCFD1, P22213

Locations in the PathwayBrowser

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Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
    - Transport to the Golgi and subsequent modification (Saccharomyces cerevisiae)
      - ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
        
        COPII-mediated vesicle transport (Saccharomyces cerevisiae)
        
        NSF ATPase activity dissociates cis-SNARE (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)
        
        cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)
        
        NSF and SNAPs bind cis-SNARE complex (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)
        
        cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)

Signal Transduction (Saccharomyces cerevisiae)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Saccharomyces cerevisiae)
  - Signaling by Rho GTPases (Saccharomyces cerevisiae)
    - RHO GTPase cycle (Saccharomyces cerevisiae)
      - RHOA GTPase cycle (Saccharomyces cerevisiae)
        
        RHOA binds effectors at the plasma membrane (Saccharomyces cerevisiae)
        
        RHOA plasma membrane effectors [cytosol] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)
        
        RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Saccharomyces cerevisiae)
        
        RHOA plasma membrane effectors [cytosol] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)

Vesicle-mediated transport (Saccharomyces cerevisiae)

- Membrane Trafficking (Saccharomyces cerevisiae)
  - ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
    - COPII-mediated vesicle transport (Saccharomyces cerevisiae)
      - NSF ATPase activity dissociates cis-SNARE (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)
        
        cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)
      - NSF and SNAPs bind cis-SNARE complex (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)
        
        cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)
        
        SLY1 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P22213

Gene Names

SLY1

Reference Genes

BioGPS Gene:851770 SLY1

ENSEMBL:YDR189W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDR189W SLY1

Monarch:851770 SLY1

NCBI Gene:851770 SLY1

SGD:YDR189W

Reference Transcript

RefSeq:NM_001180497.1 SLY1

Other Identifiers

1779575_at

6291_at

851770

GO:0000139

GO:0000149

GO:0003674

GO:0005515

GO:0005575

GO:0005737

GO:0005783

GO:0005794

GO:0005829

GO:0006886

GO:0006887

GO:0006888

GO:0006890

GO:0006904

GO:0008150

GO:0012505

GO:0015031

GO:0016020

GO:0016050

GO:0016192

GO:0019905

GO:0023052

GO:0030134

GO:0031410

GO:0033043

GO:0035543

GO:0046578

GO:0048193

GO:0048280

GO:0048284

GO:0051049

GO:0061025

Participates

as a candidate of

RHOA plasma membrane effectors [cytosol] (Saccharomyces cerevisiae)

as an output of

NSF ATPase activity dissociates cis-SNARE (Saccharomyces cerevisiae)

as a component of

BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)

Inferred From

SCFD1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_010475.1

PRO

P22213

PDB

1MQS

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q01590	5	SED5 [cytosol] (R-SCE-9613991) SED5 [ER to Golgi transport vesicle membrane] (R-SCE-5689838) SED5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-5688157) SED5 [endoplasmic reticulum membrane] (R-SCE-5689474) SED5 [Golgi membrane] (R-SCE-6807771)	0.808	7
UniProt:P41834	1	UFE1 [endoplasmic reticulum membrane] (R-SCE-2029079)	0.553	4

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