Reactome | CDK9 [nucleoplasm]

CDK9 [nucleoplasm]

Stable Identifier

R-SCE-51801

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Q03957

Locations in the PathwayBrowser

Expand all

Signal Transduction (Saccharomyces cerevisiae)

- Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
  - ESR-mediated signaling (Saccharomyces cerevisiae)
    - Estrogen-dependent gene expression (Saccharomyces cerevisiae)
      - p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Saccharomyces cerevisiae)
        
        CDK9 [nucleoplasm] (Saccharomyces cerevisiae)
        
        MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Saccharomyces cerevisiae)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Saccharomyces cerevisiae)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK9 [nucleoplasm] (Saccharomyces cerevisiae)
        
        MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Saccharomyces cerevisiae)
        
        ESR1:ESTG:P-TEFb [nucleoplasm] (Saccharomyces cerevisiae)
        
        P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK9 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:Q03957

Reference Genes

BioGPS Gene:853718

ENSEMBL:YKL139W

KEGG:sce:YKL139W

Monarch:853718

NCBI Gene:853718

SGD:YKL139W

UCSC:Q03957

Reference Transcript

RefSeq:NM_001179705.1

Other Identifiers

10734_at

1776423_at

853718

GO:0000166

GO:0000307

GO:0000790

GO:0003674

GO:0004672

GO:0004674

GO:0004693

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005737

GO:0006354

GO:0006355

GO:0006360

GO:0006366

GO:0006368

GO:0006397

GO:0006412

GO:0006413

GO:0006417

GO:0006468

GO:0006974

GO:0008024

GO:0008134

GO:0008150

GO:0008353

GO:0009891

GO:0016301

GO:0016310

GO:0016740

GO:0018105

GO:0018193

GO:0030332

GO:0031124

GO:0032786

GO:0032806

GO:0032968

GO:0043167

GO:0044212

GO:0045903

GO:0045943

GO:0045944

GO:0051726

GO:0070692

GO:0070816

GO:1902554

Participates

as an input of

Formation of P-TEFb complex (Saccharomyces cerevisiae)

as a component of

Other forms of this molecule

CDK13 [nucleoplasm]

CDK12 [nucleoplasm]

CDK13 [extracellular region]

CDK13 [ficolin-1-rich granule lumen]

Inferred From

CDK9 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_012783.1

ENSEMBL

YKL139W, YKL139W, YKL139W_mRNA

IntEnz

2.7.11.23

PRO

Q03957

PDB

7JV7

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46962	2	CTK2 [nucleoplasm] (R-SCE-51613) CTK2 [nucleoplasm] (R-SCE-51611)	0.894	13
UniProt:P46963 CTK3			0.89	13
UniProt:P25555 GBP2			0.738	4
UniProt:P38922 HRB1			0.597	3
UniProt:P11484	17	HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	2
UniProt:Q01560 NOP3			0.527	2
UniProt:P06782	5	PRKAA2 [nucleoplasm] (R-SCE-163682) PRKAA1 [cytosol] (R-SCE-380935) phospho-p-T183-PRKAA1 [cytosol] (R-SCE-380964) phospho-p-T172-PRKAA2 [cytosol] (R-SCE-200417) PRKAA2 [cytosol] (R-SCE-200405)	0.508	2