Reactome | MSG5 [nucleoplasm]

MSG5 [nucleoplasm]

Stable Identifier

R-SCE-2871619

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

DUSP6, P38590

Locations in the PathwayBrowser

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Immune System (Saccharomyces cerevisiae)

- Cytokine Signaling in Immune system (Saccharomyces cerevisiae)
  - Signaling by Interleukins (Saccharomyces cerevisiae)
    - Interleukin-17 signaling (Saccharomyces cerevisiae)
      - MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
- Innate Immune System (Saccharomyces cerevisiae)
  - Toll-like Receptor Cascades (Saccharomyces cerevisiae)
    - Toll Like Receptor 10 (TLR10) Cascade (Saccharomyces cerevisiae)
      - MyD88 cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 2 (TLR2) Cascade (Saccharomyces cerevisiae)
      - Toll Like Receptor TLR1:TLR2 Cascade (Saccharomyces cerevisiae)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
      - Toll Like Receptor TLR6:TLR2 Cascade (Saccharomyces cerevisiae)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 3 (TLR3) Cascade (Saccharomyces cerevisiae)
      - MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 4 (TLR4) Cascade (Saccharomyces cerevisiae)
      - MyD88-independent TLR4 cascade (Saccharomyces cerevisiae)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 5 (TLR5) Cascade (Saccharomyces cerevisiae)
      - MyD88 cascade initiated on plasma membrane (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Saccharomyces cerevisiae)
      - MyD88 dependent cascade initiated on endosome (Saccharomyces cerevisiae)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)
    - Toll Like Receptor 9 (TLR9) Cascade (Saccharomyces cerevisiae)
      - MyD88 dependent cascade initiated on endosome (Saccharomyces cerevisiae)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Saccharomyces cerevisiae)
        
        MAP kinase activation (Saccharomyces cerevisiae)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)

Signal Transduction (Saccharomyces cerevisiae)

- Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
  - Signaling by NTRKs (Saccharomyces cerevisiae)
    - Signaling by NTRK1 (TRKA) (Saccharomyces cerevisiae)
      - Nuclear Events (kinase and transcription factor activation) (Saccharomyces cerevisiae)
        
        ERK/MAPK targets (Saccharomyces cerevisiae)
        
        ERKs are inactivated (Saccharomyces cerevisiae)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Saccharomyces cerevisiae)
        
        ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)
        
        MSG5 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P38590

Gene Names

MSG5

Reference Genes

BioGPS Gene:855674 MSG5

ENSEMBL:YNL053W

KEGG:sce:YNL053W MSG5

Monarch:855674 MSG5

NCBI Gene:855674 MSG5

SGD:YNL053W

UCSC:P38590 MSG5

Reference Transcript

RefSeq:NM_001182892.3 MSG5

Other Identifiers

855674

GO:0000188

GO:0000754

GO:0004721

GO:0004725

GO:0005634

GO:0005737

GO:0006470

GO:0007049

GO:0007165

GO:0008138

GO:0008150

GO:0008330

GO:0016311

GO:0016787

GO:0016791

GO:0017017

GO:0033550

GO:0035335

GO:0043409

GO:0060237

GO:0071507

GO:0071554

GO:0071701

GO:0071852

GO:1903138

Participates

as a member of

ERK-specific DUSP [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

MSG5 [nucleoplasm]

Inferred From

DUSP6 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_014345.3

ENSEMBL

YNL053W, YNL053W, YNL053W_mRNA

IntEnz

3.1.3.48

PRO

P38590

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