Reactome | BMH2 [cytosol]

BMH2 [cytosol]

Stable Identifier

R-SCE-194368-2

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

YWHAE, P34730

Locations in the PathwayBrowser

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Cell Cycle (Saccharomyces cerevisiae)

- Cell Cycle Checkpoints (Saccharomyces cerevisiae)
  - G2/M Checkpoints (Saccharomyces cerevisiae)
    - G2/M DNA damage checkpoint (Saccharomyces cerevisiae)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Saccharomyces cerevisiae)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Saccharomyces cerevisiae)
        
        YWHAE dimer [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of YWHAE [cytosol] (Saccharomyces cerevisiae)
        
        BMH2 [cytosol] (Saccharomyces cerevisiae)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Saccharomyces cerevisiae)
        
        YWHAE dimer [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of YWHAE [cytosol] (Saccharomyces cerevisiae)
        
        BMH2 [cytosol] (Saccharomyces cerevisiae)

Signal Transduction (Saccharomyces cerevisiae)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Saccharomyces cerevisiae)
  - Signaling by Rho GTPases (Saccharomyces cerevisiae)
    - RHO GTPase Effectors (Saccharomyces cerevisiae)
      - RHO GTPases activate PKNs (Saccharomyces cerevisiae)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Saccharomyces cerevisiae)
        
        YWHAE dimer [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of YWHAE [cytosol] (Saccharomyces cerevisiae)
        
        BMH2 [cytosol] (Saccharomyces cerevisiae)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Saccharomyces cerevisiae)
        
        YWHAE dimer [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of YWHAE [cytosol] (Saccharomyces cerevisiae)
        
        BMH2 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P34730 BMH2

Gene Names

BMH2, YDR099W, YD8557.08

Chain

initiator methionine:1, chain:2-273

Reference Genes

BioGPS Gene:851676 BMH2

KEGG:sce:YDR099W BMH2

Monarch:851676 BMH2

NCBI Gene:851676 BMH2

UCSC:P34730 BMH2

Reference Transcript

RefSeq:NM_001180407.3 BMH2

Other Identifiers

851676

GO:0000077

GO:0000278

GO:0001402

GO:0003688

GO:0005515

GO:0005634

GO:0005737

GO:0005886

GO:0006031

GO:0006267

GO:0006270

GO:0006974

GO:0007124

GO:0007165

GO:0007265

GO:0008104

GO:0008150

GO:0030437

GO:0031397

GO:0031399

GO:0034221

GO:0043066

GO:0043934

GO:0050815

GO:0051726

GO:0070873

GO:1904667

Participates

as a member of

Homologues of YWHAE [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

BMH2 [cytosol]

Inferred From

YWHAE [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_010384.3

ENSEMBL

YDR099W, YDR099W, YDR099W_mRNA

PRO

P34730

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P39104	2	PIK1 [cytosol] (R-SCE-1604615) PIK1 [Golgi membrane] (R-SCE-1806202)	0.744	5
UniProt:P32598	1	PPP1CC [cytosol] (R-SCE-163443)	0.669	5
UniProt:Q03497	12	PAK7 [plasma membrane] (R-SCE-211555-2) PAK1 [plasma membrane] (R-SCE-3928409-2) phospho-p-S144,T423-PAK1 [plasma membrane] (R-SCE-3928472-2) PAK5 [cytosol] (R-SCE-428459-2) PAK4 [cytosol] (R-SCE-428461-2) PAK6 [cytosol] (R-SCE-428454-2) phospho-p-S154,T436-PAK3 [cytosol] (R-SCE-5357471) PAK3 [cytosol] (R-SCE-428457) PAK1 [cytosol] (R-SCE-162629-2) PAK2 [cytosol] (R-SCE-211604-2) phospho-p-S144,T423-PAK1 [cytosol] (R-SCE-399819-2) phospho-p-S141,T402-PAK2 [cytosol] (R-SCE-399824-2)	0.564	2
UniProt:P22216	2	phospho-p-S,3T-CHEK2 [nucleoplasm] (R-SCE-5683784) phospho-p-T68-CHEK2 [nucleoplasm] (R-SCE-113825)	0.499	2