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SWD3 [nucleoplasm]
Stable Identifier
R-SCE-1629838
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
Synonyms
WDR5, P38123
Locations in the PathwayBrowser
Expand all
Chromatin organization (Saccharomyces cerevisiae)
Chromatin modifying enzymes (Saccharomyces cerevisiae)
PKMTs methylate histone lysines (Saccharomyces cerevisiae)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)
Core MLL complex, SMYD3, PRDM9 [nucleoplasm] (Saccharomyces cerevisiae)
Core MLL complex [nucleoplasm] (Saccharomyces cerevisiae)
SET1A complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
SET1B complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)
SETD3, SETD7, WHSC1L1, Core MLL complex [nucleoplasm] (Saccharomyces cerevisiae)
Core MLL complex [nucleoplasm] (Saccharomyces cerevisiae)
SET1A complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
SET1B complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)
WHSC1L1, Core MLL complex, SMYD3, SETD3 [nucleoplasm] (Saccharomyces cerevisiae)
Core MLL complex [nucleoplasm] (Saccharomyces cerevisiae)
SET1A complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
SET1B complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
RMTs methylate histone arginines (Saccharomyces cerevisiae)
WDR5 binds Me2sR3-replicative histone H3 (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
WDR5:Me2sR3-histone H3 [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
Gene expression (Transcription) (Saccharomyces cerevisiae)
Epigenetic regulation of gene expression (Saccharomyces cerevisiae)
Epigenetic regulation by WDR5-containing histone modifying complexes (Saccharomyces cerevisiae)
Formation of WDR5-containing histone-modifying complexes (Saccharomyces cerevisiae)
CXXC1 and WDR82 bind SET1A complex (Saccharomyces cerevisiae)
SET1A complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
SET1A complex:WDR82:CXXC1 [nucleoplasm] (Saccharomyces cerevisiae)
SET1A complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
CXXC1 and WDR82 bind SET1B complex (Saccharomyces cerevisiae)
SET1B complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
SET1B complex:WDR82:CXXC1 [nucleoplasm] (Saccharomyces cerevisiae)
SET1B complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
Formation of the SET1A complex (Saccharomyces cerevisiae)
SET1A complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
Formation of the SET1B complex (Saccharomyces cerevisiae)
SET1B complex [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
SWD3 [nucleoplasm] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P38123
Gene Names
SWD3
Reference Genes
BioGPS Gene:852472 SWD3
ENSEMBL:YBR175W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YBR175W SWD3
Monarch:852472 SWD3
NCBI Gene:852472 SWD3
SGD:YBR175W
Reference Transcript
RefSeq:NM_001178523.1 SWD3
Other Identifiers
1771751_at
7177_at
852472
GO:0000723
GO:0000781
GO:0003674
GO:0005515
GO:0005575
GO:0005634
GO:0005694
GO:0006325
GO:0006348
GO:0008150
GO:0008168
GO:0008213
GO:0016570
GO:0016740
GO:0018193
GO:0031509
GO:0032200
GO:0042393
GO:0042800
GO:0048188
GO:0051321
GO:0051568
GO:0051726
GO:1903341
Participates
as an input of
WDR5 binds Me2sR3-replicative histone H3 (Saccharomyces cerevisiae)
as a component of
WDR5:Me2sR3-histone H3 [nucleoplasm] (Saccharomyces cerevisiae)
WRAD complex [nucleoplasm] (Saccharomyces cerevisiae)
Inferred From
WDR5 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_009734.1
PRO
P38123
PDB
6VEN
,
6BX3
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P39706
1
RBBP5 [nucleoplasm]
(R-SCE-1629836)
0.875
11
UniProt:P43132
1
ASH2L [nucleoplasm]
(R-SCE-1629834)
0.872
13
UniProt:Q03012
1
CXXC1 [nucleoplasm]
(R-SCE-535610)
0.802
10
UniProt:P38827
2
SETD1A [nucleoplasm]
(R-SCE-3239027)
SETD1B [nucleoplasm]
(R-SCE-5244714)
0.802
10
UniProt:P38337 SHG1
0.744
8
UniProt:Q03323 SDC1
0.744
8
UniProt:P36104
1
SWD2 [nucleoplasm]
(R-SCE-9821474)
0.744
5
UniProt:P15108
6
HSP90AA1 [secretory granule lumen]
(R-SCE-6801515-2)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-SCE-6801470-2)
HSP90AA1 [plasma membrane]
(R-SCE-534996-2)
HSP90AA1 [extracellular region]
(R-SCE-3221946-2)
HSP90AA1 [nucleoplasm]
(R-SCE-5082401-2)
HSP90AA1 [cytosol]
(R-SCE-192864-2)
0.564
2
UniProt:P11484
17
HSPA1L [cytosol]
(R-SCE-3371410-4)
HSPA2 [cytosol]
(R-SCE-3371408-4)
HSPA1A [cytosol]
(R-SCE-6792602-4)
HSPA6 [ficolin-1-rich granule lumen]
(R-SCE-6801512-4)
HSPA1A [ficolin-1-rich granule lumen]
(R-SCE-6801496-4)
HSPA1A [extracellular region]
(R-SCE-6805872-4)
HSPA6 [extracellular region]
(R-SCE-6806500-4)
HSPA6 [secretory granule lumen]
(R-SCE-6801472-4)
HSPA1A [nucleoplasm]
(R-SCE-6792605-4)
HSPA2 [nucleoplasm]
(R-SCE-912480-4)
HSPA1L [nucleoplasm]
(R-SCE-5082367-4)
HSPA14 [nucleoplasm]
(R-SCE-5252082-4)
HSPA6 [nucleoplasm]
(R-SCE-5252088-4)
HSPA13 [nucleoplasm]
(R-SCE-5252009-4)
HSPA14 [cytosol]
(R-SCE-5251948-4)
HSPA13 [cytosol]
(R-SCE-5251981-4)
HSPA6 [cytosol]
(R-SCE-3371521-4)
0.527
2
UniProt:P10592
20
SSA2 [cytosol]
(R-SCE-264476)
SSA2 [nucleoplasm]
(R-SCE-5082380)
SSA2 [cytosol]
(R-SCE-3371410-3)
SSA2 [cytosol]
(R-SCE-3371408-3)
SSA2 [cytosol]
(R-SCE-6792602-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801512-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801496-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801494)
SSA2 [extracellular region]
(R-SCE-6805872-3)
SSA2 [extracellular region]
(R-SCE-6806500-3)
SSA2 [extracellular region]
(R-SCE-6805936)
SSA2 [secretory granule lumen]
(R-SCE-6801530)
SSA2 [secretory granule lumen]
(R-SCE-6801472-3)
SSA2 [nucleoplasm]
(R-SCE-6792605-3)
SSA2 [nucleoplasm]
(R-SCE-912480-3)
SSA2 [nucleoplasm]
(R-SCE-5082367-3)
SSA2 [nucleoplasm]
(R-SCE-5252082-3)
SSA2 [nucleoplasm]
(R-SCE-5252088-3)
SSA2 [nucleoplasm]
(R-SCE-5252009-3)
SSA2 [cytosol]
(R-SCE-5251948-3)
0.527
2
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