Reactome | CRZ1 [nucleoplasm]

CRZ1 [nucleoplasm]

Stable Identifier

R-SCE-1592223

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

SP1, P53968

Locations in the PathwayBrowser

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Gene expression (Transcription) (Saccharomyces cerevisiae)

- RNA Polymerase II Transcription (Saccharomyces cerevisiae)
  - RNA polymerase II transcribes snRNA genes (Saccharomyces cerevisiae)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Saccharomyces cerevisiae)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        CRZ1 [nucleoplasm] (Saccharomyces cerevisiae)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        CRZ1 [nucleoplasm] (Saccharomyces cerevisiae)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Saccharomyces cerevisiae)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        CRZ1 [nucleoplasm] (Saccharomyces cerevisiae)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
        
        CRZ1 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P53968

Gene Names

CRZ1

Reference Genes

BioGPS Gene:855704 CRZ1

ENSEMBL:YNL027W

KEGG:sce:YNL027W CRZ1

Monarch:855704 CRZ1

NCBI Gene:855704 CRZ1

SGD:YNL027W

UCSC:P53968 CRZ1

Reference Transcript

RefSeq:NM_001182866.1 CRZ1

Other Identifiers

855704

GO:0000790

GO:0000978

GO:0000981

GO:0000987

GO:0001228

GO:0003674

GO:0003677

GO:0003700

GO:0005634

GO:0005737

GO:0006031

GO:0006038

GO:0006355

GO:0006357

GO:0006873

GO:0008150

GO:0008270

GO:0010765

GO:0030007

GO:0033554

GO:0042221

GO:0043167

GO:0043565

GO:0045944

GO:0046872

GO:0050801

GO:0051049

GO:0071277

GO:0071444

GO:0071467

GO:0071469

GO:0071475

GO:0071483

GO:2001040

Participates

as a component of

POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

CRZ1 [nucleoplasm]

Inferred From

SP1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_014371.1

ENSEMBL

YNL027W, YNL027W, YNL027W_mRNA

PRO

P53968

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29295	4	CSNK1D [nucleoplasm] (R-SCE-421305) CSNK1E [nucleoplasm] (R-SCE-421306) CSNK1E [cytosol] (R-SCE-205877) CSNK1D [cytosol] (R-SCE-380315)	0.527	3