RNA Polymerase III Abortive Initiation

Stable Identifier
R-SCE-111943
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
General
SVG |   | PPTX  | SBGN
RNA Polymerase III Abortive Initiation

Abortive initiation, the repetitive formation of short oligonucleotides, is a ubiquitous feature of transcriptional initiation. For pol III, it has been analyzed only in S. cerevisiae (Bhargava and Kassavetis, 1999). The released products of abortive initiation, principally di- and tri-nucleotides, indicate the participation of retractive endonucleolytic cleavage of these initially forming abortive products. The transition from abortive to productive transcription may occur at bp +5.

Literature References
PubMed ID Title Journal Year
10473618 Abortive initiation by Saccharomyces cerevisiae RNA polymerase III.

Bhargava, P, Kassavetis, GA

J Biol Chem 1999
Participants
Orthologous Events
Authored
Created
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