Reactome | RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane]

RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-RNO-983044-5

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

integral component of lumenal side of endoplasmic reticulum membrane

Synonyms

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor, D4A0E0

Locations in the PathwayBrowser

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Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Rattus norvegicus)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Budding of COPII coated vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Capturing cargo and formation of prebudding complex (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Formation of peptide loading complex (PLC) (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Loading of antigenic peptides on to class I MHC (Rattus norvegicus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Rattus norvegicus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Rattus norvegicus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
      - Transport of MHC heterotrimer to ER exit site (Rattus norvegicus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)
        
        RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D4A0E0

Gene Names

RT1-CE4

Reference Genes

ENSEMBL:ENSRNOG00000039744

Other Identifiers

10831114

10831122

17756290

17756299

414783

5712333

5781096

5816043

5820637

5824526

5875739

5875968

5943543

5954339

5965285

5984837

5985707

6005738

6026371

6068621

6073732

6080207

6124998

6183578

6196084

6476362

6545163

6558486

6651777

A_44_P440517

GO:0002376

GO:0002476

GO:0005575

GO:0005576

GO:0005615

GO:0005886

GO:0006955

GO:0008150

GO:0009897

GO:0016020

GO:0016021

GO:0019882

ILMN_1370764

Participates

as a member of

Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Rattus norvegicus)

Other forms of this molecule

RT1-CE4 [secretory granule membrane]

RT1-CE4 [azurophil granule membrane]

RT1-CE4 [phagocytic vesicle membrane]

RT1-CE4 [recycling endosome membrane]

RT1-CE4 [early endosome membrane]

RT1-CE4 [ER to Golgi transport vesicle membrane]

RT1-CE4 [plasma membrane]

RT1-CE4 [Golgi membrane]

RT1-CE4 [integral component of lumenal side of endoplasmic reticulum membrane]

RT1-CE4 [plasma membrane]

Inferred From

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

Ensembl

ENSRNOP00000059471, ENSRNOT00000064734, ENSRNOG00000039744

RGD

1598234

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