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S-Farn-HRAS [endoplasmic reticulum membrane]
Stable Identifier
R-RNO-9647788
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endoplasmic reticulum membrane
Synonyms
P20171
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAS processing (Rattus norvegicus)
ICMT methylates S-Farn RAS proteins (Rattus norvegicus)
S-Farn-RAS [endoplasmic reticulum membrane] (Rattus norvegicus)
S-Farn-HRAS [endoplasmic reticulum membrane] (Rattus norvegicus)
RCE1 cleaves S-Farn proRAS proteins (Rattus norvegicus)
S-Farn-RAS [endoplasmic reticulum membrane] (Rattus norvegicus)
S-Farn-HRAS [endoplasmic reticulum membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P20171 Hras
Gene Names
Hras, Hras1
Chain
chain:1-186, initiator methionine:, chain:2-186, propeptide:187-189
Reference Genes
BioGPS Gene:293621 Hras
KEGG Gene (Rattus norvegicus):293621 Hras
Monarch:293621 Hras
NCBI Gene:293621 Hras
UCSC:P20171 Hras
Reference Transcript
RefSeq:NM_001130441.1 Hras
RefSeq:NM_001098241.1 Hras
Participates
as a member of
S-Farn-RAS [endoplasmic reticulum membrane] (Rattus norvegicus)
Other forms of this molecule
HRAS [plasma membrane]
S-Farn-Me HRAS [plasma membrane]
S-Farn-Me PalmS HRAS [Golgi membrane]
S-Farn-Me HRAS [endoplasmic reticulum membrane]
S-Farn-proHRAS [endoplasmic reticulum membrane]
proHRAS [cytosol]
Hras [plasma membrane]
S-Farn-Me-2xPalmS HRAS [plasma membrane]
Inferred From
S-Farn-HRAS [endoplasmic reticulum membrane]
(Homo sapiens)
Modified Residues
Name
S-farnesyl-L-cysteine (farnesyl group) at 186 (in Homo sapiens)
Coordinate
186
Modification
farnesyl group
PsiMod Name
S-farnesyl-L-cysteine [MOD:00111]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine.
Cross References
RefSeq
NP_001091711.1
,
NP_001123913.1
IntEnz
3.6.5.2
PRO
P20171
RGD
2827
PDB
3V4F
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